NRI Researcher Receives Award to Further Work on Obesity and Cancer
December 1, 2015 • University of North Carolina (UNC) at Chapel Hill professor Stephen Hursting has received a prestigious National Cancer Institute (NCI) Outstanding Investigator Award (OIA), which provides stable funding for cancer research with breakthrough potential. Dr. Hursting, a professor in UNC’s Department of Nutrition, Nutrition Research Institute and Lineberger Comprehensive Cancer Center, is one of 43 researchers nationwide to receive an OIA. The grant will provide Hursting with $5.34 million over a seven-year period to further his research on the mechanistic links between obesity and cancer.
Dr. Hursting Awarded Grant from Breast Cancer Research Foundation
October 28, 2015 • The Breast Cancer Research Foundation seeks “to prevent and cure breast cancer by advancing the world’s most promising research.”Since 1993 BCRF-supported investigators have been deeply involved in every major advance in breast cancer prevention, diagnosis and treatment. In 2015-2016, BCRF is awarding $48.5 million in grants to more than 240 scientists to advance this work. Among those recipients is Stephen Hursting, Ph.D., M.P.H., Professor of Nutrition at the UNC Nutrition Research Institute.
Is Life Expectancy a Good Measure of Health?
October 27, 2015 • A recent, global study published in The Lancet (2015; 386, p.743-800) clearly emphasizes the importance of the latter referring to our quality of life. According to the Global Burden of Disease (GBD) study, worldwide life expectancy at birth rose by 6.2 years between 1990 and 2013. However, these additional years come at a price as healthy life expectancy at birth increased by only 5.4 years over the same 13 year time span.
VIP Student Journal: 2023
Our Virtual Internship Program is offered to high school students (those entering 9th grade through recent graduates entering their freshman year of college in the fall of 2023. This four-week program provides opportunities to learn from NRI principal investigators, participate in group mentoring sessions, and complete an independent nutrition research paper and presentation.
A Paper on Vitamin E
by Caroline Johnson The NRI’s fourth annual Virtual Internship Program (VIP) concluded on July 20 with 21 high school students from around the country presenting their research on the nutrients of their choice. Caroline Johnson, a rising ninth grader at Pine Lake...
Breast cancer risks and new treatment options
The combination of few treatment options and the aggressive nature of triple-negative breast cancer (TNBC) results in a higher recurrence and mortality rate. Research from the NRI seeks to understand TNBC mechanisms with the goal of directing development of...
About the NRI
Deborah F. Tate, PhD
Interim Director
Professor of Nutrition
As a trailblazer in precision nutrition research, the UNC Nutrition Research Institute investigates the intricate interplay between nutrients, lifestyle behaviors, environmental influences, genetic and other biological factors. We’re dedicated to unraveling the mysteries of nutritional diversity among individuals. By leveraging top-tier scientific minds and cutting-edge genetic, metabolic, and digital tools, we’re poised to revolutionize personalized nutrition recommendations and the behavioral support tools needed for realizing healthier futures.
Building upon our legacy as a leader in fundamental and translational science, we’re expanding our reach into human clinical and community trials. I am determined to further this expansion, ensuring that we remain at the forefront of cutting-edge research both in our laboratories and within our communities.
The NRI is forging a path towards a healthier tomorrow for generations to come. Through this website, we aim to keep you informed about our fantastic people, latest developments, participation opportunities, milestones, and community engagements.
Deborah F. Tate, PhD
Core Values
Our Core Values are the shared values to which we commit ourselves for how we conduct our work at the NRI and the way we approach our mission and vision.
Collaboration
We work together to achieve collective and individual goals because we believe that multiple perspectives promote better outcomes.
Innovation
We are innovative and compassionate in our approach to complex issues in precision nutrition.
Cultural Stewardship
We seek to respect the unique qualities of each individual and to foster an environment where open inquiry and expression by all members of this institute are embraced.
Dedication
We are determined to excel in every aspect of our research enterprise.
Integrity
We conduct ourselves with integrity in all our scientific, business and community endeavors.
Research Excellence
We are responsible for conducting publicly and privately funded innovative research with excellence.
We Develop Precision Nutrition
The UNC Nutrition Research Institute is an internationally recognized center that conducts innovative basic and translational science studying how individual differences in requirements and responses to diet affect our individual nutritional needs. We believe that our advances in nutrition science are leading to successes in preventing or mitigating the negative effects of chronic diseases and aging and in improving human development, even prior to conception. → Learn more about Precision Nutrition
UNC-Chapel Hill
The Nutrition Research Institute is part of the University of North Carolina at Chapel Hill. We’re proud of our Carolina heritage and to represent UNC on the North Carolina Research Campus in Kannapolis.
NC Research Campus
Located in Kannapolis just north of Charlotte, the North Carolina Research Campus brings together eight university research centers along with industry, government, and nonprofit partners to advance human health through nutrition. Together, scientists study precision nutrition and work to develop safer, more nutritious crops and foods.
Kannapolis, NC
Kannapolis, North Carolina, just north of Charlotte, is a growing city with deep roots in textile history and a strong focus on the future. Home to the North Carolina Research Campus, Kannapolis brings together universities, innovators, and community partners in a walkable downtown setting with parks, local dining, and year-round events.
Where We Are
UNC Nutrition Research Institute
500 Laureate Way
Kannapolis, NC 28081
704-250-5000
UNC Nutrition Research Institute
Research Spotlight
“GLP-1 medications don’t just change your appetite. They also change how your body absorbs and handles nutrients,” noted Evan Paules, PhD, postdoctoral research fellow. “As these medications become more widely used, we need to understand how they might shift nutrient needs, including choline, so we can keep people healthy while they are on them.”
Research that transforms lives.
PUBLICATIONS FROM OUR RESEARCHERS
Precision Nutrition Training and Mentoring
Research Spotlight
Evaluating the Evolving Real-World Adverse Events of GLP-1RAs Using FDA Adverse Event Reporting System (FAERS)
NRI Contributor: Stephen D. Hursting, PhD, MPH
Obesity remains one of the most urgent public health challenges of our time, contributing to conditions such as type 2 diabetes, cardiovascular disease, and cancer.
GLP-1 receptor agonists have emerged as promising tools for obesity and weight management, offering new opportunities to improve cardiometabolic health. But as their use grows, so does the need to better understand their safety in real-world settings.
Research that transforms lives.
PUBLICATIONS FROM OUR RESEARCHERS
Nutri-epigenetics of Mitochondrial Function and Energy Homeostasis in Obesity
How nutrition-related epigenetic changes may disrupt mitochondrial function and energy homeostasis, helping drive obesity beyond the effects of genetics, diet, and physical activity alone.
Choline, Lipidomics, and MASLD: Insights From the CARDIA Study
Certain blood lipids and choline-related metabolites were linked to fatty liver disease, suggesting they may help explain risk and serve as possible biomarkers.
Holding the Line: Preventing Weight Gain in Emotional Eaters
Weight gain prevention is a critical component of comprehensive obesity care. Emotional eating may contribute to unwanted weight gain, increasing cardiometabolic risk factors among adults with obesity.