Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity

February 21, 2020 | News, pub-genotype, pub-zeisel, pub-zeisel-genotype, Zeisel News

February 24, 2020 -People differ in their requirements for and responses to nutrients and bioactive molecules in the diet. Many inputs contribute to metabolic heterogeneity (including variations in genetics, epigenetics, microbiome, lifestyle, diet intake, and environmental exposure).

A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.

August 29, 2019 | pub-genotype, pub-sumner, pub-sumner-genotype

Metabolomics reveals new mechanisms for pathogenesis in Barth syndrome and introduces novel roles for cardiolipin in cellular function.

August 28, 2019 | pub-genotype, pub-pathmasiri, pub-pathmasiri-genotype, pub-sumner, pub-sumner-genotype

Choline: The Underconsumed and Underappreciated Essential Nutrient.

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-environment

Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort.

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-environment, pub-zeisel-genotype

Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups.