Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
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April 25, 2016 • Watch Stephen Hursting, Ph.D., M.P.H. discuss his research on Fox 46.
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April 12, 2016 • Cashew Chipolte Crema recipe designed by Chef Megan Lambert, Senior Instructor at Johnson & Wales University.
April 2016
Anti-Inflammatory Diet May Fight Breast Cancer Promising work is underway in the laboratory of Dr. Stephen Hursting at the NRI to identify dietary interventions that can reduce the risk of cancer. Omega-3 fatty acids are well known anti-inflammatory dietary...
Study Finds Weight Loss Amount is More Important than Diet Type in Reversing Obesity-Cancer Link
March 28, 2016 • Researchers striving to break the link between obesity and cancer have found in a new preclinical study that significant weight loss through calorie restriction, but not moderate weight loss through a low-fat diet, was linked to reduced breast cancer growth. The preliminary findings (abstract #4321) will be presented from 1-5 p.m. April 19 at the 2016 American Association for Cancer Research Annual Meeting in New Orleans.
Anti-Inflammatory Diet May Fight Breast Cancer
March 28, 2016 • Promising work is underway in the laboratory of Dr. Stephen Hursting at the NRI to identify dietary interventions that can reduce the risk of cancer. Omega-3 fatty acids are well known anti-inflammatory dietary supplements. Because inflammation is associated with cancer, Hursting is investigating whether these supplements can reduce risk of developing cancer.