Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
Excess exposure to insulin may be the primary cause of insulin resistance
Excess exposure to insulin may be the primary cause of insulin resistance
Wenhong Cao, Hui-Yu Liu, Tao Hong, Zhenqi Liu
Am J Physiol Endocrinol Metab. 2010 February; 298(2): E372. doi: 10.1152/ajpendo.00677.2009
PMCID: PMC2822476
New Faculty – Stephen Hursting, Ph.D., M.P.H.
The NRI is pleased to welcome Stephen Hursting, Ph.D., M.P.H., to its faculty. Dr. Hursting, an expert in diet and cancer prevention, trained at UNC Chapel Hill and directed research programs for 20 years at the National Cancer Institute and University of Texas. He...
Bonsai Expo, December 6 and 7
Bonsai aficionados will converge in Kannapolis at the North Carolina Research Campus this weekend, December 6 and 7 for the second annual Winter Silhouette Bonsai Expo. The ancient art of bonsai–the word means to plant in a container–is sometimes best appreciated when...
When Chimps Outperform Humans
From the desk of: Carol L. Cheatham, Ph.D. As a developmental cognitive neuroscientist, I’m always interested in learning about studies that will inform my work. Recently, I attended the International Conference on Infant Studies where I heard a scientist speak about...
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The following has been reprinted from Charlotte Observer, an article by Lisa Thornton. By the time they celebrate the North Carolina Research Campus’ seventh anniversary next year, leaders say, 10 buildings will have been erected on campus, and another two nearby. The...
NRI joins fellow institutions in marking six years at the North Carolina Research Institute
The following has been reprinted from Independent Tribune, an article by Michael Knox. KANNAPOLIS, N.C. — To mark the North Carolina Research Campus’ sixth anniversary, academic and scientific leaders touted advances made at the Kannapolis complex and offered a...