Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study
Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study.
Miller CA, Corbin KD, da Costa KA, Zhang S, Zhao X, Galanko JA, Blevins T, Bennett BJ, O’Connor A, Zeisel SH.
Am J Clin Nutr. 2014 Sep;100(3):778-86. doi: 10.3945/ajcn.114.087692. Epub 2014 Jun 18.
PMID: 24944063
A small amount of dietary carbohydrate can promote the HFD-induced insulin resistance to a maximal level
A small amount of dietary carbohydrate can promote the HFD-induced insulin resistance to a maximal level.
Mei S, Yang X, Guo H, Gu H, Zha L, Cai J, Li X, Liu Z, Bennett BJ, He L, Cao W.
PLoS One. 2014 Jul 23;9(7):e100875. doi: 10.1371/journal.pone.0100875. eCollection 2014.
PMID: 25055153
Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery
Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery.
Albright J, Quizon PM, Lusis AJ, Bennett BJ.
BMC Med Genomics. 2014 Aug 12;7:51. doi: 10.1186/1755-8794-7-51.
PMID: 25115202
Responsiveness of cardiometabolic-related microbiota to diet is influenced by host genetics
Responsiveness of cardiometabolic-related microbiota to diet is influenced by host genetics.
O’Connor A, Quizon PM, Albright JE, Lin FT, Bennett BJ.
Mamm Genome. 2014 Aug 27. [Epub ahead of print]
PMID: 25159725
Dietary intake, nutrition, and fetal alcohol spectrum disorders in the Western Cape Province of South Africa
May, PA, Hamrick, KJ, Corbin, KD, Hasken, JM, Marais, AS, Brooke, LE, Blankenship, J, Hoyme, HE, Gossage, JP. (2014) Dietary intake, nutrition and fetal alcohol spectrum disorders in the Western Cape Province of South Africa.
October 2014
SoundBites is the NRI’s monthly e-newsletter. This month features Folami Ideraabdullah’s environmental lecture held at Catawba College and Dr. Zeisel’s input on a new research publication about gut microbes.