Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
Appetite for Life SoundBites Summer 2013
In this issue:
First comprehensive nutrigenetics book published
2013 Appetite for Life highlights
Art contest and N.C. Science Festival
Faculty News and Meet the People Behind the Science: Jody Albright, Research Asst.
Additions to Our Team
Student-led IMPACT Program
Catawba College Transfers Scientific Instruments to NRI
When Catawba College transferred state-of-the-art instrumentation to the NRI, it opened the door to expanding research capabilities for NRI scientists and real-life lab experience for Catawba students. The NRI will use the equipment to further its research into how metabolism and nutrition requirements are individualized.
Helping the world get healthier, one person at the time
May 31, 2013 – Researchers at the NRI are studying nutrition in a new way, discovering how diet and exercise affect health and help prevent chronic disease. Strengthened associations between individualized nutrition and enhanced health will have a global impact.
Dr. Philip May awarded $5.3M grant to study FASD
The National Institute of Health’s National Institute on Alcohol Abuse and Alcoholism awarded NRI Research Scientist Philip May, Ph.D. a $5.3 million grant to study Fetal Alcohol Spectrum Disorders in South Africa .
Dr. Martin Kohlmeier honored with Weinsier Award
Martin Kohlmeier, M.D., Ph.D., faculty member at the NRI, received the 2013 Roland L. Weinsier Award for Excellence in Medical/Dental Nutrition Education from the American Society for Nutrition (ASN).
NRI Director receives prestigious Greenberg Award
Stephen H. Zeisel, M.D., Ph.D., Kenan Distinguished University Professor in Nutrition and Pediatrics and UNC NRI Director, was the 2012 recipient of the Bernard G. Greenberg Alumni Endowment Award from the UNC Gillings School of Public Health. Dr. Zeisel was recognized for excellence in service to the public health community.