Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
Help Make People Healthier through Science
Postdoctoral Research Associate-Sumner Lab
The NRI and this position are in Kannapolis, NC, in the Charlotte region. Position Summary The Sumner Lab is seeking a Postdoctoral Research Associate with graduate experience in NMR spectroscopy and mass spectrometry to join our team and conduct metabolomics...
We’re looking for a mural artist
The City of Kannapolis and the UNC Nutrition Research Institute, as lead partners in a NC Research Campus collaboration for the NC Science Festival, are issuing a Call for Design Proposals. North Carolina artists (high school age and beyond) are invited to submit a...
Appetite for Life: Better Health Outcomes, Survey
New Optimism for Breaking the Obesity-Cancer Link
by Violet Kiesel, PhD Obesity is a major problem. Having obesity increases risk of developing serious chronic diseases like cancer, which can reduce quality of life and lifespan. This risk becomes more striking when considering the growing number of people who are...
Precision nutrition improves health at individual level, expert says
Susan Sumner, PhD, is a professor of Nutrition and pharmacology at the UNC Nutrition Research Institute. Using state-of-the-art metabolomics and exposome technologies, Sumner’s team determines how molecules that are present in our tissues and biological fluids are...