Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Environment and Nutrition Publications
Functional Connectivity and Metabolic Alterations in Medial Prefrontal Cortex in a Rat Model of Fetal Alcohol Spectrum Disorder: A Resting-State Functional Magnetic Resonance Imaging and in vivo Proton Magnetic Resonance Spectroscopy Study. Mooney S
October 25, 2016 • According to the CDC, sugar-sweetened beverages are the largest source of added sugar in the average American’s diet, and the Dietary Guidelines for Americans recommend individuals consume no more than ten percent of calories per day from processed or added sugar. From the UNC Chapel Hill Nutrition Research Institute (NRI), scientists are investigating the connection between these beverages, human genetics, and uric acid metabolism.
August 2, 2016 • Two NRI investigators are among six recipients of recent seed-funding vouchers awarded by the Duke University MURDOCK Study, a research partner of the North Carolina Research Campus (NCRC) in Kannapolis. Saroja Voruganti, PhD, and Manya Warrier, PhD, each received $10,000 to help pay for the services and capabilities of the David H. Murdock Research Institute, located on the NCRC, which offers scientific expertise and advanced instrumentation to collaborators focused on transforming science at the intersection of human health, nutrition and agriculture.
Unrelated Diseases Can Share Common Underlying Genetic Factors A recent study by NRI researcher Saroja Voruganti and her laboratory highlights the value of genome-wide analysis and underscores the reality that seemingly unrelated diseases often share common,...
July 21, 2016 • A recent study by NRI researcher Saroja Voruganti and her laboratory highlights the value of genome-wide analysis and underscores the reality that seemingly unrelated diseases often share common, underlying factors. In their recent publication (Chittoor et al., 2016) the researchers identified two genes, ITPR1 and CNTN4, as potential mediators of uric acid concentration. Notably, neither of these genes shows an obvious connection to uric acid, but they have been linked to autism and other neurological disorders.
December 21, 2015 • While drinking at least eight glasses of water a day may not be necessary under normal conditions, maintaining adequate hydration, especially during physical exertion in warm weather, is essential for optimal health.
Saroja Voruganti, Ph.D.