Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
Congratulations to the NRI’s Newest Doctoral Graduates
The Nutrition Research Institute has two reasons to be extra thankful this holiday season: we are celebrating two new PhDs! Congratulations to Kaylee Helfrich, PhD, and Evan Paules, PhD, our most recent NRI doctoral graduates. Kaylee Helfrich, PhD, (Smith Lab)...
AFL Program Summaries October 2021 – May 2022
Appetite For Life programs may be presented in person and/or virtually. To stay informed about upcoming events and other news from the Nutrition Research Institute, visit our website, subscribe to our emails, and follow us on social...
Innovation. Discovery. Impact.
Fiscal Year 2021 was a landmark year in the history of the UNC Nutrition Research Institute: We transitioned directorship while continually adapting to safety requirements to operate our world-class center during a worldwide pandemic. We are delighted to share with...
Student Success at the NRI: Alleigh Wiggs, Breast Cancer Researcher and Advocate
Congratulations to Alleigh Wiggs, a student researcher with the Sumner Lab, whose research on the effects of diet and exercise on endogenous estrogens and subsequent breast cancer risk in postmenopausal women was recently published in Frontiers in Endocrinology....
Dr. Susan M. Smith Named Inaugural Dickson Foundation – Harris Teeter Distinguished Professor in Nutrition
Susan M. Smith, PhD, has been named the inaugural holder of The Dickson Foundation – Harris Teeter Distinguished Professorship in Nutrition. Smith, who joined the UNC-Chapel Hill faculty in 2016, is a professor of Nutrition at the Gillings School of Global Public...
Metabolic clues could serve as early predictors of pregnancy complications, inform nutritional intervention
Published on the Gillings School of Global Public Health website June 18, 2021. Some of the most common complications that moms and babies face during pregnancy include high blood pressure, preeclampsia and preterm birth, but predicting who might be at risk is still...