Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
November 2019
Saroja Voruganti, PhD, Promoted to Associate Professor October 22, 2019 – Saroja Voruganti, PhD, was recently promoted to the rank of Associate Professor in the Department of Nutrition at the University of North Carolina at Chapel Hill. Nutrition Research Institute...
October 2019
Choline must be integrated into the prenatal supplement regimen, says expert review September 16, 2019 – This article was published originally on nutraingredients-usa.com on September 11, 2019. By Stephen Daniels The importance of choline during the first 1,000 days...
Hursting moves into 16th year of Breast Cancer Research Foundation grant
September 17, 2019 – “Our work has evolved from asking Is obesity increasing cancer risk? and What are the mechanisms linking obesity and cancer?” he says. “We have largely answered the first question and are still working on the second, but our focus really has turned to What are we going to do about it?”
Choline must be integrated into the prenatal supplement regimen, says expert review
This article was published originally on nutraingredients-usa.com on September 11, 2019. By Stephen Daniels The importance of choline during the first 1,000 days after conception is increasingly understood by the medical community, and dietary supplement manufacturers...
Fish Oil Supplement Study
Study Purpose: to test for the effects of a fatty acid supplement in human heath. Recruiting: Healthy* males and females ages 30-80 for up to 12 weeks. *No smoking, substance abuse, pregnancy or breast feeding, history of diabetes, cholesterol medications, or...