Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
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Check www.charlottesgotalot.com for a calendar of events. The Charlotte region has several huge festivals that draw crowds worldwide annually. Downtown Charlotte Carolina Panthers Stadium Charlotte Hornets Arena Charlotte Checkers Charlotte Knights (minor league...
Startup SNP Therapeutics Merges Gene Testing With Personalized Nutrition
July 15, 2019 – In what may be the ultimate affirmation of “you are what you eat,” an innovative Charlotte-area company is merging high-tech genomic testing with personalized nutritional formulations to treat individual medical conditions.
Zeisel Presents Before NIH
Nutrition Research Institute (NRI) Director Steven Zeisel, MD, PhD, recently presented before the National Institutes of Health (NIH) Nutrition Research Task Force (NRTF). The NRTF was established in October 2016 to coordinate and accelerate progress in nutrition...
July 2019
Chinese herb may be a natural method of treating diabetes June 28, 2019 –The traditional Chinese herb Lycii Cortex (LyC), with its powerful compound kukoamine B, could be an effective nutraceutical choice for lowering blood glucose when used alone or in combination...
What should I eat on my night shift?
June 11, 2019 -Martin Kohlmeier, MD, PhD, director of the Human Research Core at the University of North Carolina’s Nutrition Research Institute, says, “The effect of a disrupted sleep cycle on energy metabolism is real but of modest size. In the end, it’s about the practicalities of food access, convenience, and the time demands of the shift. Planning ahead is your friend.