Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
Eggs May Enhance Infant Brain Development, Researchers Find
June 29, 2018 – Early introduction of eggs boosts infant blood concentrations of several key indicators of brain development, a recent study in Ecuador found. The results could have implications for infant nutrition in both the developing and developed worlds.
Genetic Factors in Determining Bone Mass
June 29, 2018 – Osteoporosis is a serious public health concern and causes significant economic burden. Currently, about 54 million people in the United States have osteoporosis or low bone mass. It is projected that by 2025, the incidences of bone fracture will be 3 million, resulting in about $25 billion in medical costs each year. Among different ethnicities, Hispanics are estimated to have the most rapid increase in osteoporosis burden by 2025.
Breastfeeding and Maternal Alcohol Use: Prevalence and Effects on Child Outcomes and Fetal Alcohol Spectrum Disorders
Fetal Alcohol Spectrum Disorders and Assessment of Maxillary and Mandibular Arc Measurements
AFL Program Summaries September 2017-May 2018
Appetite For Life - September 27, 2017, with Folami Ideraabdullah, PhD: "Vitamin D and Human Health: 10 Things Your Mother Never Told You". Vitamin D is an essential vitamin linked to human health and diseases such as cancer, diabetes, and heart disease. It occurs...
June 2018
NRI Included in UNC Creativity Hubs Inaugural Award to Study Obesity May 30, 2018 – Five NRI faculty members are among a team of UNC researchers receiving an award to study one of the world's most pressing issues: the obesity epidemic. The cross-disciplinary team,...