Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Blueberry Chocolate Bark
July 25, 2016 • Blueberry Chocolate Bark by Chef Aubrey Mast of the NC State Plants for Human Health Institute.
Unrelated Diseases Can Share Common Underlying Genetic Factors
July 21, 2016 • A recent study by NRI researcher Saroja Voruganti and her laboratory highlights the value of genome-wide analysis and underscores the reality that seemingly unrelated diseases often share common, underlying factors. In their recent publication (Chittoor et al., 2016) the researchers identified two genes, ITPR1 and CNTN4, as potential mediators of uric acid concentration. Notably, neither of these genes shows an obvious connection to uric acid, but they have been linked to autism and other neurological disorders.
July 2016
The Sweet Reality of Eating Nutritious Fruits This time of year, fresh fruits abound. No matter whether the fruit you eat is fresh, canned, frozen, or dried, all of the varieties offer a plethora of flavors, colors and, most importantly, health benefits. No...
NRI welcomes renowned scientist to Kannapolis institute
June 27, 2016 • The UNC Nutrition Research Institute (NRI) welcomes Susan Smith, Ph.D., who joins the research facility’s roster of scientists this month. Dr. Smith is an internationally recognized expert on how nutrition affects birth defect risks.
The Sweet Reality of Eating Nutritious Fruits
June 23, 2016 • This time of year, fresh fruits abound. No matter whether the fruit you eat is fresh, canned, frozen, or dried, all of the varieties offer a plethora of flavors, colors and, most importantly, health benefits.
Faculty and Research Opportunities
June 22, 2016 • The UNC Nutrition Research Institute offers opportunities for faculty and researchers to refine or expand a nutrition-related research program. The Institute is particularly interested in research related to nutrigenomics, metabolomics, epigenetics, clinical nutrition and/or energy expenditure.
Learn more about Faculty Fellows and Visiting Scholars.