Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
August 2015
August 2015 SoundBites features: Healthy Eyes at Every Age, Last Chance to Tour the NRI, and Cooking for Nourishment: Demo + Talk
Healthy Eyes at Every Age
July 22, 2015 • Speakers at the recent Institute of Food Technologists meeting in Chicago in July discussed an essential nutrient that plays a vital role in human health. Unfortunately, few people have heard of it and fewer still are eating enough of it.
“Choline is an essential but widely under-consumed nutrient,” says Catherine Adams Hutt, registered dietician and science and nutrition advisor to The Choline Information Council®. “Only children typically get enough choline and most adults, including pregnant and lactating women, don’t get as much choline as they need. Just as choline is essential in the development of the brain, it is also critical for the development of the mechanics of our eyes,” she adds.
The “-omics” of Nutrient Metabolism
July 1, 2015 • How our bodies use the nutrients that nourish us drives much of the science at the Nutrition Research Institute. Recent advances in nutrition studies have shed light on the metabolic fates of nutrients and about the molecular actors and mechanisms responsible for the underlying processes. A major reason for the explosive advances in the understanding of nutrient metabolism has been the massive investigative use of all kinds of “-omics,” new fields of study for the mining of data-rich biological information.
Go With Your Gut: How a community of trillions affects your individual health
July 1, 2015 • Everyday we learn more about how the gut microbiome may influence health. Our gut microbial community—a super-organism, with trillions of members—has been associated with obesity, diabetes, cancer, heart disease, and immune disorders, and even moods. These findings have generated enormous enthusiasm among researchers and the lay public, as they suggest a largely untapped area for health-promoting interventions. One mechanism through which the gut microbiome may affect health is through the metabolism of food and nutrients.
Choline, Cognition and You: The Essential Nutrient for Maximum Brain Power
ESCONDIDO, Calif., June, 23, 2015 /PRNewswire/ -- Choline is critical to overall health and healthy cognitive function. This essential nutrient has an impact on the brain throughout our lives. Choline intake early in life supports the brain as it ages, preventing...
Taco Truck
Juan Taco, our favorite food truck, is coming back to the NRI! All NRI employees are invited to enjoy freshly made chicken, beef or veggie tacos to celebrate the arrival of Spring! Employee of the Quarter Award winner will be announced. One food ticket per person...