Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
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NRI Faculty Member Receives Prestigious Award
Philip A. May, Ph.D., is this year’s recipient of the Henry Rosett Award, in recognition of his substantial contribution researching the field of Fetal Alcohol Spectrum Disorders (FASD). Dr. May received the award at the annual meeting of the FASD Study Group of the Research Society on Alcoholism in June.
Three Parent Baby Possible in Two Years
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Pave the Way to a Healthier Future
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Phosphatidylcholine Supplementation in Pregnant Women Consuming Moderate-Choline Diets Does Not Enhance Infant Cognitive Function
Cheatham, C.L., Goldman, B.D., Fischer, L.M., da Costa, K-A, Reznick, S., Zeisel, S.H. (2012) Phosphatidylcholine supplementation in pregnant women consuming moderate choline diets does not enhance infant cognitive function: a randomized double-blind placebo-controlled trial. American Journal of Clinical Nutrition. doi: 10.3945/ajcn.112.037184.