Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Early-Life Predictors of Fetal Alcohol Spectrum Disorders
January 22, 2020 – The clinical teams at the UNC Nutrition Research Institute and in South Africa led by principal investigator Philip A. May, PhD have published findings of a decade-long effort to drive down the age at which the diagnosis of fetal alcohol spectrum disorders (FASD) can be made in affected children. The paper, “Early-Life Predictors of Fetal Alcohol Spectrum Disorders” is published in Pediatrics.
January 2020
NRI Congratulates First-time First-authors December 2019 –Agatha Christie once said, “The first time you do a thing is always exciting.” Well, we’ve had a lot of excitement at the Nutrition Research Institute recently! Two members of the Smith Lab are celebrating...
AFL Program Summaries September 2019 – May 2020
Appetite For Life – Wednesday, September 18, 2019: “Good Bowls: A social venture to improve healthy food access” was presented by Alice Ammerman, DrPH, Mildred Kaufman Distinguished Professor of Nutrition, Gillings School of Global Public Health, and Director of the...
Important NIH Award for NRI and Partners
December 12, 2019 – Agatha Christie once said, “the first time you do a thing is always exciting.” Well, we’ve had a lot of excitement at the Nutrition Research Institute recently! Two members of the Smith Lab are celebrating becoming first-time first-authors of scientific journal publications.
NRI Congratulates First-time First-Authors
December 12, 2019 – Agatha Christie once said, “the first time you do a thing is always exciting.” Well, we’ve had a lot of excitement at the Nutrition Research Institute recently! Two members of the Smith Lab are celebrating becoming first-time first-authors of scientific journal publications.
Choline: The forgotten vital nutrient we’re not getting enough of
November 14, 2019 – Eating a plant-based diet? You may be low on choline. Standard nutritional advice to cut down on meat and dairy may be stopping us getting enough of an essential nutrient named choline. Should we be worried?