Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Obesity increases mortality and modulates the lung metabolome during pandemic H1N1 influenza virus infection in mice
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in NOD mice
Metabolites as Biomarkers of Adverse Reactions Following Vaccination: A Pilot Study using Nuclear Magnetic Resonance Metabolomics.
Stable isotope resolved metabolomic differences between hormone-responsive and triple-negative breast cancer cell lines.
A metabolomics approach to investigate kukoamine B – a potent natural product with anti-diabetic properties.
Recap: 2019 Nutrigenetics, Nutrigenomics and Precision Nutrition Short Course
Participants from around the world attended the NRI’s fourth consecutive Nutrigenetics, Nutrigenomics, and Precision Nutrition Short Course from June 3 – 6 in Kannapolis on the North Carolina Research Campus. Known as “NGx,” the 4-day, workshop-style course provides...