Microbiome and Nutrition

The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.

Publications

 

Microbiome and Nutrition Publications

2020

Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K

2019

Association of dietary patterns with the gut microbiota in older, community-dwelling men.  Meyer K

The impact of early-life sub-therapeutic antibiotic treatment (STAT) on excessive weight is robust despite transfer of intestinal microbes.  Sumner S

Protein Intake at Twice the RDA in Older Men Increases Circulatory Concentrations of the Microbiome Metabolite Trimethylamine-N-Oxide (TMAO).  Zeisel S

2018

Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.  Meyer K

Human microbiota, blood group antigens, and disease.  Sumner S

2017

Dietary Choline and Betaine and Risk of CVD: A Systematic Review and Meta-Analysis of Prospective Studies.  Meyer K

A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation.  Sumner S

Metabolic profiling of a chronic kidney disease cohort reveals metabolic phenotype more likely to benefit from a probiotic.  Sumner S

Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease.  Zeisel S

2016

Microbiota-Dependent Metabolite Trimethylamine N-Oxide and Coronary Artery Calcium in the Coronary Artery Risk Development in Young Adults Study (CARDIA).  Meyer K

Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk.  Meyer K

Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S

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Infant Nutrition and Cognition Study

Study Purpose: The purpose of this research study is to determine if eating eggs during breastfeeding will improve nutrient content of milk and infant cognition. Recruiting: Healthy lactating women at 12-15 weeks postpartum What participants will do: You and your...

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US Post Office Kannapolis Library Kannapolis Parks & Recreation Shopping Oak Avenue Mall – 0.7 miles – within walking distance to NRI 358 Oak Ave Mall Dr, Kannapolis , NC 28081 Contains Grocery (Food Lion), Discount (Family Dollar), and Restaurants (Subway, Pizza...

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Long-term American Homes 4 Rent Atlantic American (Castle & Cooke) Coopers Ridge Apartments Integra Springs Apartments at Kellswater Legacy Grand at Concord Apartments The Ridges Apartments Vida Apartments Inform landlord that you are employed at UNC Chapel Hill...

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Some notable nearby area hospitals include: Atrium Health-NorthEast Medical Center 920 Church Street N, Concord, NC 28025 704-403-3000 Carolinas Healthcare System Kannapolis 2711 Lane Street, Kannapolis, NC 28081 704-403-3000 Novant Health Presbyterian Medical Center...

Services

City of Kannapolis Customer Service Center 401 Laureate Way (First Floor, City Hall & Police Headquarters) Monday through Friday, 8:00 a.m. to 5:00 p.m., except City holidays 704-920-4399 For one resource with everything below and more, see the Kannapolis, NC...