Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
February 2019
The Choices I.C.A.N. Make January 25, 2019 – Pregnant women are often consumed by dietary choices such as finding a great prenatal vitamin, eating foods that will promote fetal growth, and doing everything they can to protect their pregnancy. After delivery, however,...
January 2019
Offspring Brain Health Determined by Maternal Diet and Genes December 12, 2018 – The importance of choline to brain development and function was first demonstrated in the 1980s, but because choline has multiple fates and functions within the body, the question of how...
Offspring Brain Health Determined by Maternal Diet and Genes
December 12, 2018 – The importance of choline to brain development and function was first demonstrated in the 1980s, but because choline has multiple fates and functions within the body, the question of how choline levels specifically impacted neural development has remained unanswered. In research just published in The FASEB Journal, NRI director Steven Zeisel, MD PhD, and NRI assistant professor Natalia Surzenko, PhD, make a major contribution towards answering this question.
December 2018
Starving Cells May Lead to New Cancer Treatments November 20, 2018 –Nutrient availability regulates cell metabolism, growth, and survival. When nutrients are in short supply, cells can pause their growth or even eliminate themselves through a process known as...
November 2018
Choline in Human Milk Plays a Crucial Role in Infant Memory October 30, 2018 – Choline is present in human milk, and is especially important for fetal and infant development [2,3]. “The hint that choline is important for infant development comes from the fact that in...
October 2018
Celebrating a Decade of Nutrition Discoveries September 28, 2018 – This October, the NRI proudly marks its tenth anniversary of delving into the science of Precision Nutrition. What began in 2008 with two faculty members and a supporting staff of nine is, today, a...