Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
New Grant to Study Nutrition and Chemotherapeutic Response
May 30, 2018 – Delisha Stewart, PhD, Assistant Professor of Nutrition at the UNC Nutrition Research Institute, has been awarded a two year grant to study the impact of diet on chemotherapeutic treatment resistance in obesity-driven, aggressive breast cancer. This award builds from the research Dr. Stewart has conducted over the last ten years.
NRI Included in UNC Creativity Hubs Inaugural Award to Study Obesity
May 14, 2018 – Five NRI faculty members are among a team of UNC researchers receiving an award to study one of the world’s most pressing issues: the obesity epidemic. The cross-disciplinary team, known as the Heterogeneity in Obesity Creativity Hub, will leverage the strengths of Carolina’s schools of medical and health sciences, affiliated research centers and institutes, and prowess in big data management to take a novel approach to assess the underlying causes of obesity to unlock new, targeted ways to treat the disease.
May 2018
The Connection Between Diet, Obesity and Cancer April 30, 2018 –Obesity prevalence in the US has tripled over the last 50 years. In 2016, a report by the International Agency for Research on Cancer highlighted that excess body fatness increases the risk for 13 types...
The connection between diet, obesity, and cancer: Nutrition experts explore the evidence
April 26, 2018 -About one third of cancer cases are estimated to be linked to dietary and other modifiable risk factors, especially for obesity-related cancers such as breast, colorectal, ovarian, endometrial, kidney, gallbladder, esophageal, and pancreatic cancers. In this special theme issue of the Journal of the Academy of Nutrition and Dietetics, food and nutrition practitioners and other health professionals take an in-depth look at the relationship between nutrition, obesity, and cancer prevention, treatment, and survival and identify research gaps for future prevention research efforts.
NRI Expert Discusses Genetics and Weight Loss in Prevention Magazine
April 26, 2018 – Joanne Laird had struggled with obesity for her entire life. She’d tried every diet under the sun, but it wasn’t until last June, when she received the results of an at-home DNA test, that she was finally able to shed the extra pounds.
AFL@JWU Recipes – April 18
April 18, 2018 – Chef Megan Lambert, MS, RD, Senior Instructor in College of Culinary Arts at Johnson & Wales University, Charlotte, prepared healthy, delightful recipes with chicken while Steph Saullo, MS, RD of the UNC Nutrition Research Institute, shared nutrition information on each recipe. The recipes from the April 18, 2018 Appetite For Life are available here for your cooking enjoyment!