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Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups.

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-environment, pub-zeisel-genotype

Genetic Signatures in Choline and 1-Carbon Metabolism

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-genotype

Corbin, K. D., Abdelmalek, M. F., Spencer, M. D., da Costa, K. A., Galanko, J. A., Sha, W., Suzuki, A., Guy, C. D., Cardona, D. M., Torquati, A., Diehl, A. M., and Zeisel, S. H. (2013) Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. FASEB J 27, 1674-1689

Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction.

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-genotype

Dietary Choline Requirements of Women Effects of Estrogen and Genetic Variation

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-genotype

Fischer, L.M., da Costa, K-A, Kwock, L., Galanko, J., Zeisel, S.H. (2010) Dietary choline requirements of women: effects of estrogen and genetic variation. American Journal of Clinical Nutrition. 92(5):1113-19. PMCID: PMC2954445.

Choline Intake and Genetic Polymorphisms Influence Choline Metabolite Concentrations in Human Breast Milk and Plasma

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-genotype

Fischer, L.M., daCosta, K-A, Galanko, J., Sha, W., Stephenson, B., Vick, J., Zeisel, S.H. (2010) Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma. American Journal of Clinical Nutrition. 92(2): 336-346. PMCID: PMC2904035.

Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute.

August 22, 2019 | pub-exposome, pub-french, pub-french-environment

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity.

August 22, 2019 | pub-exposome, pub-french, pub-french-environment, pub-french-genotype, pub-genotype

Carcinogenicity of benzene

August 22, 2019 | pub-exposome, pub-french, pub-french-environment

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