Precision Nutrition Needed for Healthy Military Muscles

July 27, 2017 • “Eat colorful meals and make sure you get enough choline.” That’s the key advice offered by David Nieman, Dr.PH, FACSM, Director of the Appalachian State University Human Performance Laboratory; and Steven Zeisel, M.D., Ph.D., Director of the University of North Carolina at Chapel Hill’s Nutrition Research Institute. during lunch at the Medical, BioMedical & BioDefense: Support the Warfighter symposium in Chapel Hill in June. These were among several surprising findings […]

Cheatham Named to Education Board

July 27, 2017 – Carol L. Cheatham, PhD, has been selected to join the Education Board at the American Health Council. The council, comprising leaders and contributors from all areas of healthcare, is America’s leading organization in health awareness and advancement. Dr. Cheatham will share her knowledge and expertise on the effects of nutrition on brain development and function. […]

Choline Biomarker Study Call for Participants

August 28, 2017 – The Zeisel Lab at the NRI is recruiting participants for a clinical study on the essential nutrient choline. The lab needs healthy females and males between the ages of 17 and 70 to take part in a six-week study. Participants will be asked to provide blood samples and will eat meals provided by the NRI during the course of the study. “Healthy” means normal body weight, and no smoking, drug abuse, unusual diets, allergy to soy, or chronic diseases.  All qualifying participants will be paid when they complete the study.

Your Generosity Fuels Tomorrow’s Discoveries

Your Generosity Fuels Tomorrow’s Discoveries

Curiosity. Intellect. Altruism.   At the Nutrition Research Institute (NRI), our pursuit of groundbreaking nutrition solutions is fueled by the relentless spirit of discovery, the ability to empower young minds, and the transformation these individuals bring to...

Experts Say More Research Is Needed to Understand Obesity-Cancer Link

Experts Say More Research Is Needed to Understand Obesity-Cancer Link

This article originally appeared on PharmacyTimes.com. Written by: Aislinn Antrim, Assistant Managing Editor Evidence has shown that reversing pro-cancer effects requires significant weight loss as well as substantial metabolic reprogramming. Although weight loss can...

NRI-Hosted Symposium on Future Directions in Choline

NRI-Hosted Symposium on Future Directions in Choline

First established as an essential nutrient in 1998, choline is a nutrient with critical roles in the health and development of the brain, liver, and more. The past 25 years have seen significant advances in the choline field, however, the question remains: What’s...

About the NRI

Deborah F. Tate, PhD
Interim Director
Professor of Nutrition 

As a trailblazer in precision nutrition research, the UNC Nutrition Research Institute investigates the intricate interplay between nutrients, lifestyle behaviors, environmental influences, genetic and other biological factors. We’re dedicated to unraveling the mysteries of nutritional diversity among individuals. By leveraging top-tier scientific minds and cutting-edge genetic, metabolic, and digital tools, we’re poised to revolutionize personalized nutrition recommendations and the behavioral support tools needed for realizing healthier futures.

Building upon our legacy as a leader in fundamental and translational science, we’re expanding our reach into human clinical and community trials. I am determined to further this expansion, ensuring that we remain at the forefront of cutting-edge research both in our laboratories and within our communities.

The NRI is forging a path towards a healthier tomorrow for generations to come. Through this website, we aim to keep you informed about our fantastic people, latest developments, participation opportunities, milestones, and community engagements.

Deborah F. Tate, PhD

Core Values

Our Core Values are the shared values to which we commit ourselves for how we conduct our work at the NRI and the way we approach our mission and vision.

Collaboration

We work together to achieve collective and individual goals because we believe that multiple perspectives promote better outcomes.

Innovation

We are innovative and compassionate in our approach to complex issues in precision nutrition.

Cultural Stewardship

We seek to respect the unique qualities of each individual and to foster an environment where open inquiry and expression by all members of this institute are embraced.

Dedication

We are determined to excel in every aspect of our research enterprise.

Integrity

We conduct ourselves with integrity in all our scientific, business and community endeavors.

 

Research Excellence

We are responsible for conducting publicly and privately funded innovative research with excellence.

We Develop Precision Nutrition

The UNC Nutrition Research Institute is an internationally recognized center that conducts innovative basic and translational science studying how individual differences in requirements and responses to diet affect our individual nutritional needs. We believe that our advances in nutrition science are leading to successes in preventing or mitigating the negative effects of chronic diseases and aging and in improving human development, even prior to conception.        → Learn more about Precision Nutrition

UNC-Chapel Hill

The Nutrition Research Institute is part of the University of North Carolina at Chapel Hill. We’re proud of our Carolina heritage and to represent UNC on the North Carolina Research Campus in Kannapolis.

NC Research Campus

Located in Kannapolis just north of Charlotte, the North Carolina Research Campus brings together eight university research centers along with industry, government, and nonprofit partners to advance human health through nutrition. Together, scientists study precision nutrition and work to develop safer, more nutritious crops and foods.

Kannapolis, NC

Kannapolis, North Carolina, just north of Charlotte, is a growing city with deep roots in textile history and a strong focus on the future. Home to the North Carolina Research Campus, Kannapolis brings together universities, innovators, and community partners in a walkable downtown setting with parks, local dining, and year-round events.

Where We Are

UNC Nutrition Research Institute

500 Laureate Way
Kannapolis, NC 28081
704-250-5000

UNC Nutrition Research Institute

Research Spotlight

Choline, GLP-1s, and the Future of Precision Nutrition
“GLP-1 medications don’t just change your appetite. They also change how your body absorbs and handles nutrients,” noted Evan Paules, PhD, postdoctoral research fellow. “As these medications become more widely used, we need to understand how they might shift nutrient needs, including choline, so we can keep people healthy while they are on them.”

Precision Nutrition Training and Mentoring

The NRI is a center for precision nutrition training through programs for graduate and medical students, post-doctoral trainees, faculty, practicing physicians and other medical providers, registered dietitians, and industry professionals.

Research Spotlight

Evaluating the Evolving Real-World Adverse Events of GLP-1RAs Using FDA Adverse Event Reporting System (FAERS)
NRI Contributor: Stephen D. Hursting, PhD, MPH 

Obesity remains one of the most urgent public health challenges of our time, contributing to conditions such as type 2 diabetes, cardiovascular disease, and cancer.

GLP-1 receptor agonists have emerged as promising tools for obesity and weight management, offering new opportunities to improve cardiometabolic health. But as their use grows, so does the need to better understand their safety in real-world settings.

Research that transforms lives.
PUBLICATIONS FROM OUR RESEARCHERS

Nutri-epigenetics of Mitochondrial Function and Energy Homeostasis in Obesity

NRI Contributors: Saroja Voruganti, PhD and Lydia Goss, MS, RD

How nutrition-related epigenetic changes may disrupt mitochondrial function and energy homeostasis, helping drive obesity beyond the effects of genetics, diet, and physical activity alone.

Choline, Lipidomics, and MASLD: Insights From the CARDIA Study

NRI Contributors: Katie Meyer, ScD, MPH and Anju Lulla, PhD

Certain blood lipids and choline-related metabolites were linked to fatty liver disease, suggesting they may help explain risk and serve as possible biomarkers.

Holding the Line: Preventing Weight Gain in Emotional Eaters

NRI Contributors: Rachel Goode, PhD, MPH, LCSW, Deborah Tate, PhD, Ramine Alexander, PhD, MPH, Tyisha Harper, MBA, Julian Robles, Ana Paola Campos

Weight gain prevention is a critical component of comprehensive obesity care. Emotional eating may contribute to unwanted weight gain, increasing cardiometabolic risk factors among adults with obesity.