One Size Won’t Fit All

One Size Won’t Fit All

August 20, 2019 – Nearly 35 percent of Americans are considered obese — a diagnosis that has become so common the American Medical Association recognizes it as a chronic disease. While the diagnosis is the same for all, the treatments vary; what works for one person typically doesn’t work for another. In response, researchers from across UNC have joined forces to tackle this ever-growing problem.

Breaking the Link Between Obesity, Gastrointestinal Cancers

Breaking the Link Between Obesity, Gastrointestinal Cancers

October 3, 2018 – UNC NRI’s and UNC Lineberger’s Stephen Hursting, PhD, MPH, along with Cornelia Ulrich, PhD, MS, the director of the Huntsman Cancer Institute’s National Cancer Institute-designated Comprehensive Cancer Center, and colleagues, reviewed findings from research looking at the biological links between obesity and cancers of the colon, rectum, pancreas, liver, esophagus, gallbladder and stomach, as well as published studies on how diet, exercise, weight loss surgery, and other weight-related interventions may help reverse this connection.

Leptin’s Role in Cancer Susceptibility

Leptin’s Role in Cancer Susceptibility

August 30, 2018 – While the link between obesity and breast cancer risk is well known, the underlying mechanisms are not fully understood. Obesity alters many conditions in cells and within the body, and it is not easy to determine which of these conditions are important to the obesity-cancer link. Consequently, it is very difficult to identify potential therapeutic targets.