pub-zeisel | UNC NRI

Choline: The Underconsumed and Underappreciated Essential Nutrient.

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-environment

Choline.

August 27, 2019 | pub-zeisel

Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort.

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-environment, pub-zeisel-genotype

Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups.

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-environment, pub-zeisel-genotype

Genetic Signatures in Choline and 1-Carbon Metabolism

August 27, 2019 | pub-genotype, pub-zeisel, pub-zeisel-genotype

Corbin, K. D., Abdelmalek, M. F., Spencer, M. D., da Costa, K. A., Galanko, J. A., Sha, W., Suzuki, A., Guy, C. D., Cardona, D. M., Torquati, A., Diehl, A. M., and Zeisel, S. H. (2013) Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. FASEB J 27, 1674-1689

Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction.