Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
Nourishment Tours – June 7 at 1 PM
New Assay Tested for Antioxidant-based Products
March 10, 2016 • A team of researchers from the University of North Carolina’s Chapel Hill Nutrition Research Institute (UNC NRI) created and tested what it believes is a more reliable method to measure antioxidant capacity.
Currently, many assays involved hydrogen atom transfer reactions (like in oxygen radical absorbance capacity [ORAC] and total radical trapping antioxidant parameter [TRAP]) or electron transfer. The UNC assay measures the activation of antioxidant response elements (AREs). AREs are said to turn on genes in the body that make enzymes for protecting cells against free radical damage.
Nutrition Roadmap Aims to Advance Research to Provide More Individualized Advice
March 7, 2016 • The Interagency Committee on Human Nutrition Research (ICHNR) released the first Nutrition Research Roadmap designed to guide federal nutrition research. The 2016-2021 National Nutrition Research Roadmap encourages an increased focus on research that can lead to more individualized advice for promoting health and preventing disease.
Doctoral student wins award for papers in Nutrition Research journal
March 7, 2016 • Daniel Lupu, MD, doctoral student in nutrition, has received the 2015 David Kritchevsky Graduate Student Award from the journal Nutrition Research for two articles published in the November 2015 issue of the journal.
March 2016
March is National Nutrition Month National Nutrition Month is about focusing attention on the importance of making informed food choices and developing sound eating and physical activity habits. At the Nutrition Research Institute, we study nutrigenetics to find out...
Avocado Chocolate Mousse
February 22, 2016 • Avocado Chocolate Mousse recipe designed by Chef Megan Lambert, Senior Instructor at Johnson & Wales University.