Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
September 2020
Precision Nutrition–the Answer to "What to Eat to Stay Healthy" August 28, 2020 – From an opinion paper in the Journal of the American Medical Association by Griffin P. Rodgers, MD, and Francis S. Collins, MD, PhD for NIH. The long-recognized centrality and importance...
Research Uncovered: Baba Mass
This article was published originally by endeavors on August 19th, 2020. Baba Mass is a research technician in the Voruganti Lab within the UNC Nutrition Research Institute. He studies how genes and diet impact serum uric acid levels – a chemical created when the body...
Precision Nutrition—the Answer to “What to Eat to Stay Healthy”
This article was published originally online in the Journal of the American Medical Association on August 7, 2020. By Griffin P. Rodgers, MD and Francis S. Collins, MD, PhD, National Institutes of Health, Bethesda, MD The long-recognized centrality and importance of...
Matching Meals to Metabolism
This article was originally published on knowablemagazine.org on July 28, 2020. By Jyoti Madhusoodanan Q&A with nutrition researcher Steven Zeisel Genes, microbes and other factors govern how each person’s body processes nutrients. Understanding the connections...
August 2020
What I Learned About Nutrition Risks for COVID-19 July 30, 2020 – by Martin Kohlmeier, MD, PhD I am just reading that the Director-General of the World Health Association, Tedros Adhanom Ghebreyesus told a briefing that the Covid-19 pandemic "is not even close to...
July 2020
Voruganti to Advance Research on Childhood Obesity with NIH Grant June 30, 2020 – NRI principal investigator Saroja Voruganti, PhD, has received a 2020 Cross Border Collaboration Award from the Center for Global Health Studies (CGHS) at the National Institutes of...