Natalia Krupenko, PhD

Associate Professor of Nutrition

Natalia Krupenko, PhD, Associate Professor of Nutrition, joined the UNC Nutrition Research Institute in April 2014. Dr. Krupenko’s research is focused on the role of folate (vitamin B9) in promoting health and preventing disease in humans. Folate deficiency has been connected with increased risk for neural tube defects, cardiovascular disease and cancer. Recently, however, concerns have been raised regarding the adverse effects of over-supplementation with the vitamin. Dr. Krupenko’s goal is to determine the best ways to utilize health-protective properties of folate and prevent the possibility of its adverse effects in humans. Dr. Krupenko’s work is covered in 35 peer-reviewed publications in high impact journals and numerous presentations at national and international conferences and meetings. Dr. Krupenko earned her doctorate degree in bioorganic chemistry from the Institute of Bioorganic Chemistry, Byelorussian Academy of Sciences, in Minsk, Belarus.  She was a recipient of the Rockefeller Foundation Fellowship in Population Sciences and served on the faculty of the Medical University of South Carolina. Currently, in addition to her role at the NRI, Dr. Krupenko holds her appointment as an Associate Professor with the Department of Nutrition at the Gillings School of Global Public Health, UNC-Chapel Hill.

In the News

Natalia Krupenko, PhD, Promoted to Associate Professor of Nutrition

Natalia Krupenko, PhD, has been promoted to the rank of Associate Professor in the Department of Nutrition at the University of North Carolina at Chapel Hill. Nutrition Research Institute (NRI) Director Steven Zeisel, MD, PhD, announced the promotion with great...

September Faculty Focus: Natalia Krupenko, PhD

Bold Questions, Breakthrough Answers For some, it would be difficult to leave the idyllic coastal city of Charleston, South Carolina behind for small town life in Kannapolis, North Carolina. That wasn’t the case for Natalia Krupenko, PhD. As she interviewed to join...

Starving Cells May Lead to New Cancer Treatments

November 20, 2018 – Nutrient availability regulates cell metabolism, growth, and survival. When nutrients are in short supply, cells can pause their growth or even eliminate themselves through a process known as programmed cell death, thereby protecting the health of the organism as a whole. If nutrient deprivation happens at certain critical periods, such as during the rapid growth of the embryonic brain, severe developmental consequences can arise (this is why proper maternal nutrition is so important). In contrast, harnessing the innate ability of cells to enter programmed cell death is an important strategy in cancer treatment.

Pregnancy, Drinking and Diet: Consider "Whole Health" When Pregnant

February 18, 2016 • Scientists at the UNC Chapel Hill Nutrition Research Institute are developing a “whole health” message for pregnant mothers emphasizing evidence-based, nutritional research that empowers them to make their own decisions on everything from drinking to dietary choices.