Sergey A. Krupenko, PhD
Professor of Nutrition
sergey_krupenko@unc.edu
704-250-5053

Amira Abdellatef, PhD, MS
Postdoctoral Research Associate, S. Krupenko Lab
Amira A. Abdellatef is currently working as a Post-Doctoral Research Associate at Sergey A. Krupenko Lab, Nutrition Research Institute (NRI), the University of North Carolina at Chapel Hill. Dr. Amira completed her Ph.D. in cancer biology and immunology from the Graduate School of Medicine and Pharmaceutical Sciences, the University of Toyama, Japan in 2021, under the supervision of Prof. Yoshihiro Hayakawa. Before joining NRI, she completed her Research Scholar training at the University of Toyama, Japan, and a postdoctoral appointment at Julius L. Chambers Biomedical/Biotechnology Research Institute (BBRI), North Carolina Central University (NCCU), under the mentorship of Prof. Xiaohe Yang. She is a recent recipient of the Award of Female Researchers of the University of Toyama, Japan. Her research project focuses on the function of folate enzymes ALDH1L1 and ALDH1L2 in cellular metabolism and their association with human diseases. Her project utilizes cell culture and mouse models to answer questions about the role of folate metabolizing enzymes and dietary folate in liver and brain functions, tumorigenesis, cancer progression, and metastasis. She has co-authored many peer-reviewed articles and had several poster/oral presentations at international and local conferences. Outside of the academia, she enjoys listening to music, watching movies, walking, swimming, and cooking.

Halle Fogle
Graduate Student, S. Krupenko Lab
Halle earned a Bachelor’s of Science in Biology and Minor in Anthropology at St. Mary’s College of Maryland in May 2020. After moving to Charlotte, Halle joined the NRI in August 2020 as a Research Technician in Dr. Sergey Krupenko’s Lab, where she studies the role of folate in liver function and cancer disease. Halle plans to further her education in the research field within the next couple of years.
Diet and Extension of Lifespan
Life expectancy keeps growing in developed countries, approaching 90 years on average in some. There is a forecast that more than 50 percent of girls born in the U.S. after 2010 will live to become 100 years or even older, and that the first person to live up to 150 years has already been born.
Sergey A. Krupenko, Ph.D.
Sergey A. Krupenko, Ph.D., joined the UNC Nutrition Research Institute (NRI) in 2014. Dr. Krupenko’s research focuses on vitamin folate and its role in liver function and cancer disease. His goal is to understand how we can fight cancer by controlling the diet and...
2024
2023
2022
2021
2019
The Role of Single-Nucleotide Polymorphisms in the Function of Candidate Tumor Suppressor ALDH1L1.
Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver.
Deleterious mutations in ALDH1L2 suggest a novel cause for neuro-ichthyotic syndrome.
Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression.