Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Kannapolis' North Carolina Research Campus foresees growth
The following has been reprinted from Charlotte Observer, an article by Lisa Thornton. By the time they celebrate the North Carolina Research Campus’ seventh anniversary next year, leaders say, 10 buildings will have been erected on campus, and another two nearby. The...
NRI joins fellow institutions in marking six years at the North Carolina Research Institute
The following has been reprinted from Independent Tribune, an article by Michael Knox. KANNAPOLIS, N.C. — To mark the North Carolina Research Campus’ sixth anniversary, academic and scientific leaders touted advances made at the Kannapolis complex and offered a...
Kannapolis Rotary Club's Gift of $63,500
The Kannapolis Rotary Club has given a gift of $63,500 to the NRI in support of student housing. On Veteran’s Day, NRI Director Steven Zeisel, M.D., Ph.D., received a symbolic check for this donation from Kannapolis club president Jeremy Tutt and club member William...
February 17, 2015
The Role of Genetics and Other Biological Factors in the Obesity Epidemic Karen Corbin, Ph.D., R.D., joined the UNC Nutrition Research Institute (NRI) in 2009 and was promoted to research assistant professor in 2011. Dr. Corbin’s research focuses on nutritional and...
November 2014
Fetal Alcohol Spectrum Disorders More Prevalent Than Expected The following, reprinted from HealthDay in an article by Tara Haelle, reveals the findings of a study conducted by NRI Researcher Professor Philip May, Ph.D. Although drinking during pregnancy has long been...
More Kids Harmed by Drinking in Pregnancy Than Expected, Study Reports
The following, reprinted from HealthDay in an article by Tara Haelle, reveals the findings of a study conducted by NRI Research Professor Philip May, Ph.D. MONDAY, Oct. 27, 2014 (HealthDay News) – Although drinking during pregnancy has long been considered taboo, new...
