Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Wenhong Cao, M.D.
Wenhong Cao, M.D. joined the UNC Nutrition Research Institute (NRI) as a Research Associate Professor in July 2012, moving his research program from the UNC-Chapel Hill main campus to Kannapolis. For over two decades, Dr. Cao has been trying to find new and more...
Brian Bennett, Ph.D.
Brian J. Bennett, Ph.D., joined the UNC Nutrition Research Institute (NRI) in 2011 as assistant professor. Dr. Bennett researches genetic susceptibility to cardiovascular disease and obesity and investigates the effects of diet on these metabolic diseases. His work...
Timeline
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Perinatal Epigenetic Determinants of Cognitive and Metabolic Disorders
Lupu, Daniel S, Tint, Diana, Niculescu, Mihai D. Perinatal Epigenetic Determinants of Cognitive and Metabolic Disorders. Aging and Disease Vol. 2 No. 5; 1-10.
Highlights of the 2012 Research Workshop Using Nutrigenomics and Metabolomics in Clinical Nutrition Research
Zeisel, S.H., Waterland, R.A., Ordovas, J.M., Muoio, D., Jia, W., Fodor, A. (2012) Highlights of the 2012 Research Workshop: Using Nutrigenomics and Metabolomics in Clinical Nutrition Research. Journal of Parenteral and Enteral Nutrition. doi: 10.1177/0148607112462401.
