Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation.
Oleinik NV, Helke KL, Kistner-Griffin E, Krupenko NI, Krupenko SA.
J Biol Chem. 2014 Sep 19;289(38):26383-94. doi: 10.1074/jbc.M114.569657. Epub 2014 Aug 1.
PMID: 25086046
Molecular mechanisms underlying the potentially adverse effects of folate.
Strickland KC, Krupenko NI, Krupenko SA.
Clin Chem Lab Med. 2013 Mar 1;51(3):607-16. doi: 10.1515/cclm-2012-0561. Review.
PMID: 23241610
ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A.
Oleinik NV, Krupenko NI, Krupenko SA.
Oncogene. 2010 Nov 25;29(47):6233-44. doi: 10.1038/onc.2010.356. Epub 2010 Aug 23.
PMID: 20729910
Phylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymes.
Strickland KC, Holmes RS, Oleinik NV, Krupenko NI, Krupenko SA.
Chem Biol Interact. 2011 May 30;191(1-3):122-8. doi: 10.1016/j.cbi.2010.12.025. Epub 2011 Jan 6.
PMID: 21215736
ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.
Krupenko NI, Dubard ME, Strickland KC, Moxley KM, Oleinik NV, Krupenko SA.
J Biol Chem. 2010 Jul 23;285(30):23056-63. doi: 10.1074/jbc.M110.128843. Epub 2010 May 24.
PMID: 20498374
Acyl carrier protein-specific 4′-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase.
Strickland KC, Hoeferlin LA, Oleinik NV, Krupenko NI, Krupenko SA.
J Biol Chem. 2010 Jan 15;285(3):1627-33. doi: 10.1074/jbc.M109.080556. Epub 2009 Nov 20.
PMID: 19933275
Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6.
Hoeferlin LA, Fekry B, Ogretmen B, Krupenko SA, Krupenko NI.
J Biol Chem. 2013 May 3;288(18):12880-90. doi: 10.1074/jbc.M113.461798. Epub 2013 Mar 21.
PMID: 23519469