The Lifespan Impact of Prenatal Alcohol Exposure

June 22, 2022 | Mooney News, News, pub-mooney, pub-smith, publications, Smith News

Fetal alcohol spectrum disorders (FASDs) encompass a range of behavioral, cognitive, and physiological impairments that result from prenatal alcohol exposure (PAE). FASD is usually diagnosed in early childhood, but while these impairments persist into adulthood,...

Incorporating genetic diversity into animal model studies of precision nutrition

March 25, 2021 | News, pub-smith, Smith News

One of the barriers to translating research results from pre-clinical to clinical is when positive results seen in animal models fail to be apparent in humans. Many early-stage studies use a single mouse strain. These mice are genetically homogeneous, and while this...

Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis

May 17, 2017 | pub-exposome, pub-smith, pub-smith-environment

An evolutionarily conserved mechanism of calcium-dependent neurotoxicity in a zebrafish model of fetal alcohol spectrum disorders

August 3, 2016 | pub-exposome, pub-smith, pub-smith-environment

CaMKII represses transcriptionally active β-catenin to mediate acute ethanol neurodegeneration and can phosphorylate β-catenin

August 3, 2016 | pub-exposome, pub-smith, pub-smith-environment

Genomic factors that shape craniofacial outcome and neural crest vulnerability in FASD

August 3, 2016 | pub-smith, pub-smith-genotype