Natalia Krupenko, PhD

Associate Professor of Nutrition

Natalia Krupenko, PhD, Associate Professor of Nutrition, joined the UNC Nutrition Research Institute in April 2014. Dr. Krupenko’s research is focused on the role of folate (vitamin B9) in promoting health and preventing disease in humans. Folate deficiency has been connected with increased risk for neural tube defects, cardiovascular disease and cancer. Recently, however, concerns have been raised regarding the adverse effects of over-supplementation with the vitamin. Dr. Krupenko’s goal is to determine the best ways to utilize health-protective properties of folate and prevent the possibility of its adverse effects in humans. Dr. Krupenko’s work is covered in 35 peer-reviewed publications in high impact journals and numerous presentations at national and international conferences and meetings. Dr. Krupenko earned her doctorate degree in bioorganic chemistry from the Institute of Bioorganic Chemistry, Byelorussian Academy of Sciences, in Minsk, Belarus.  She was a recipient of the Rockefeller Foundation Fellowship in Population Sciences and served on the faculty of the Medical University of South Carolina. Currently, in addition to her role at the NRI, Dr. Krupenko holds her appointment as an Associate Professor with the Department of Nutrition at the Gillings School of Global Public Health, UNC-Chapel Hill.

Krupenko’s Team

Madeline Hall Childress : Graduate Student, N. Krupenko Lab

Madeline Hall Childress

Graduate Student, N. Krupenko Lab

Madeline joined the NRI in March 2019 and began her doctoral studies in fall 2020. She completed her undergraduate program at the University of Alabama, where she graduated in 2018 with a major in Biology and minors in Chemistry and Spanish. Madeline works with Dr. Natalia Krupenko to research the role of folate in promoting human healthy and preventing disease.

madeline_hall@unc.edu

In the News

Starving Cells May Lead to New Cancer Treatments

Starving Cells May Lead to New Cancer Treatments

November 20, 2018 – Nutrient availability regulates cell metabolism, growth, and survival. When nutrients are in short supply, cells can pause their growth or even eliminate themselves through a process known as programmed cell death, thereby protecting the health of the organism as a whole. If nutrient deprivation happens at certain critical periods, such as during the rapid growth of the embryonic brain, severe developmental consequences can arise (this is why proper maternal nutrition is so important). In contrast, harnessing the innate ability of cells to enter programmed cell death is an important strategy in cancer treatment.

Pregnancy, Drinking and Diet: Consider "Whole Health" When Pregnant

February 18, 2016 • Scientists at the UNC Chapel Hill Nutrition Research Institute are developing a “whole health” message for pregnant mothers emphasizing evidence-based, nutritional research that empowers them to make their own decisions on everything from drinking to dietary choices.

Folate – friend or foe?

Folate – friend or foe?

January 28, 2016 • Cereal, pasta, bread, cookies – what do they have in common? The answer is “folic acid,” a synthesized form of a naturally occurring B vitamin called folate. Folate occurs naturally in some foods such as green leafy vegetables, avocados, red meat and lentils. Almost any processed food made with flour has folic acid.

Vitamins and Healthy Diet

Dr. Natalia Krupenko addresses vitamin supplementation and its effects on the human body.