Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Preterm neonatal urinary renal developmental and acute kidney injury metabolomic profiling: an exploratory study.
Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice.
Impact of a Western Diet on the Ovarian and Serum Metabolome
The continuum of fetal alcohol spectrum disorders in a community in South Africa: Prevalence and characteristics in a fifth sample.
Healthy Cooking for the Holidays: Recipes
November 16, 2016 • Appetite for Life is a series of community programs produced by the NRI brings the latest nutrition science research down to earth in educational and interactive lectures, demonstrations and events. NRI and JWU collaborated to bring the Cooking for Nourishment Demo, Healthy Cooking for the Holidays. See the recipes here.
Mom’s Diet Can Affect Development of Next Two Generations
November 17, 2016 • Nutritional deficiencies during pregnancy can have lasting effects across generations that impact development not only of children, but also of grandchildren. These heritable effects are linked to epigenetic changes that affect gene expression but not DNA sequence. At the NRI, we seek to understand how nutrition affects health and why different people respond differently to the same nutrients.