Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Meet Manya Warrier, Ph.D.
June 2, 2015 • Dr. Warrier joins the NRI this month as our newest faculty member. Her research focus is the “browning” of fat and its effects on metabolism and obesity.
Your Nutritional Needs Are as Unique as You Are
June 1, 2015 • There is mounting evidence that small amounts of essential nutrients like choline and folate have a big impact on human health. However, nutritional studies that attempt to quantify the effects of essential nutrients often produce unclear or contradictory results.
There are several reasons for this, but chief among them is the assumption that all of us process food exactly the same way. This is simply not the case. No one is metabolically identical or even similar to anyone else – not even identical twins. We all require different amounts of specific nutrients and vitamins. Scientists at the UNC Nutrition Research Institute believe this common misconception is responsible for so many contradictory study results.
June 2015
June 16, 2015 • This month’s SoundBites features an article that describes how your genetic makeup effects your nutritional needs, everything you’ve ever needed to know about vitamin supplementation, and introduces our newest faculty member, Manya Warrier, Ph.D.