Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Doctoral student wins award for papers in Nutrition Research journal
March 7, 2016 • Daniel Lupu, MD, doctoral student in nutrition, has received the 2015 David Kritchevsky Graduate Student Award from the journal Nutrition Research for two articles published in the November 2015 issue of the journal.
March 2016
March is National Nutrition Month National Nutrition Month is about focusing attention on the importance of making informed food choices and developing sound eating and physical activity habits. At the Nutrition Research Institute, we study nutrigenetics to find out...
Avocado Chocolate Mousse
February 22, 2016 • Avocado Chocolate Mousse recipe designed by Chef Megan Lambert, Senior Instructor at Johnson & Wales University.
Nutrient Deprivation Kills Kidney Cancer Cells
February 18, 2016 • The greedy metabolism of cancer cells to target kidney cell carcinomas, which kill more than 100,000 Americans each year, has been exploited by researchers. The team showed that the majority of renal cell cancers rewire their metabolism in a way that leaves them addicted to the nutrient cystine. By depriving the cancer cells of cystine, the researchers were able to trigger a form of cell death called necrosis in tumor cells.
Pregnancy, Drinking and Diet: Consider "Whole Health" When Pregnant
February 18, 2016 • Scientists at the UNC Chapel Hill Nutrition Research Institute are developing a “whole health” message for pregnant mothers emphasizing evidence-based, nutritional research that empowers them to make their own decisions on everything from drinking to dietary choices.
Dr. Philip May on Time Warner Cable News
February 17, 2016 • Watch an interview with Dr. Philip May on Time Warner Cable News. Dr. May is an expert in the field of Fetal Alcohol Spectrum Disorders (FASD) and the epidemiology of a number of health-related behaviors.