Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Gut Microbiome, Diet and Health
March 28, 2018 – At the NRI, we are conducting pioneering research on the interplay of diet and the gut microbiome in human health. The gut microbiome is a complex community of microorganisms living in our lower intestine; although we have long known of its existence, recent technological advances have allowed us to begin to define the composition and function of this dynamic community. This growing body of research demonstrates vast biologic activity within the gut microbiota, which may have the potential to affect our physiology and help guide health recommendations and interventions. Continue Reading Gut Microbiome, Diet and Health
Study focuses on child obesity
February 28, 2018 – Childhood obesity may no longer be a new concept, but the prevalence is higher than ever, and statistics show that Cabarrus County sits above the national and state averages for kids who are dangerously overweight.
An ongoing study at the N.C. Research Campus in Kannapolis hopes to take a dive into children’s health and nutrition and what might lead some to gain excess weight and others not to. The children’s health study is currently looking for children and their families to participate. Continue Reading Study focuses on child obesity
March 2018
NRI Scientist's Research Reveals Important Statistics: FASD Prevalent in US February 26, 2018 –A new study of more than 6,000 first-graders across four U.S. communities has found that a significant number of the children have fetal alcohol spectrum disorders (FASD),...
Should You Exercise When You’re Sick?
February 26, 2018 – ASU Human Performance Lab Director David Nieman, DrPH, was featured in a Time article discussing exercise and the immune system. “Your immune system needs activity to do its job better. Every time you exercise, you increase the circulation of important immune cells.” However, he emphasizes, that while “exercise is great for prevention, it’s not as helpful when you’re already sick.” Continue Reading Should You Exercise When You’re Sick?
Do you have the cure for the common cold?
February 26, 2018 – Everyone gets the common cold; hence, its name. Why isn’t there a cure or preventative vaccine? Actually there is, and you have it already – an active lifestyle including regular physical activity. David Nieman, DrPH, FACSM, the director of the Appalachian State University Human Performance Laboratory at the NC Research Campus, explains. Continue Reading Do you have the cure for the common cold?
Choline Biomarker Study Wins Federal Support
February 7, 2018 – UNC Nutrition Research Institute director Steven H. Zeisel, MD, PhD has been awarded a four-year, $2.6 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the National Institutes of Health, to develop and validate a panel of laboratory tests that can assess choline status in humans. Continue Reading Choline Biomarker Study Wins Federal Support





