News
Our research not only influences the scientific community, but the general public as well. We strive to share our discoveries with everyone. Read some of our latest articles on what is happening at the Nutrition Research Institute.
Choline: An Essential Nutrient
Makes Babies Smarter, Keeps Memory Keen and Prevents Disease, Yet Most Americans Are Missing Out
Choline was discovered in 1862, but scientists did not fully understand its importance—or what foods contained it—for another 136 years. They thought we could make our own choline, much like we make Vitamin D from sunlight and cholesterol, but only women who still produce estrogen can make enough choline—and only if they have the right genes. Forty-five percent of child-bearing women have a genetic variation called a SNP (pronounced “snip”) that prevents them from turning estrogen into choline.
Diet and Extension of Lifespan
Life expectancy keeps growing in developed countries, approaching 90 years on average in some. There is a forecast that more than 50 percent of girls born in the U.S. after 2010 will live to become 100 years or even older, and that the first person to live up to 150 years has already been born.
February 2015
Choline: An Essential Nutrient Makes Babies Smarter, Keeps Memory Keen and Prevents Disease, Yet Most Americas Are Missing Out Choline was discovered in 1862, but scientists did not fully understand its importance—or what foods contained it—for another 136 years. They...
Virtual Appetite for Life Seminars
The live stream video will begin when the event starts. To watch directly on YouTube click the link below. Link will only become active the day of the event. Hit play at or just before the scheduled event time. Cooking Demo + Talk at Johnson and Wales University,...
Clinical Studies at the NRI
The Nutrition Research Institute is committed to conducting innovative, basic and translational science to support the understanding of individualized nutrition. These advances in science promote the prevention and reduction of chronic disease and obesity. To move...
NRI Faculty Elected as AHA Fellow
The NRI is proud to announce that Saroja Voruganti, Ph.D., assistant professor in the Department of Nutrition at UNC Chapel Hill, has been elected a Fellow with the American Heart Association. Dr. Voruganti is one of 17 American Heart Association Fellows from several...
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Tsybovsky Y, Malakhau Y, Strickland KC, Krupenko SA.
Chem Biol Interact. 2013 Feb 25;202(1-3):62-9. doi: 10.1016/j.cbi.2012.12.015. Epub 2013 Jan 5.
PMID: 23295222
JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1
JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1.
Prakasam A, Ghose S, Oleinik NV, Bethard JR, Peterson YK, Krupenko NI, Krupenko SA.
Cell Death Dis. 2014 Jul 31;5:e1358. doi: 10.1038/cddis.2014.316.
PMID: 25077544
A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization
A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization.
DebRoy S, Kramarenko II, Ghose S, Oleinik NV, Krupenko SA, Krupenko NI.
PLoS One. 2013 Jul 30;8(7):e70062. doi: 10.1371/journal.pone.0070062. Print 2013.
PMID: 23936142