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Our research not only influences the scientific community, but the general public as well. We strive to share our discoveries with everyone. Read some of our latest articles on what is happening at the Nutrition Research Institute.
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Phosphatidylcholine Supplementation in Pregnant Women Consuming Moderate-Choline Diets Does Not Enhance Infant Cognitive Function
Cheatham, C.L., Goldman, B.D., Fischer, L.M., da Costa, K-A, Reznick, S., Zeisel, S.H. (2012) Phosphatidylcholine supplementation in pregnant women consuming moderate choline diets does not enhance infant cognitive function: a randomized double-blind placebo-controlled trial. American Journal of Clinical Nutrition. doi: 10.3945/ajcn.112.037184.
Choline Metabolism Provides Novel Insights into Non-Alcoholic Fatty Liver Disease and its Progression
Corbin, KD, Zeisel, SH. (2012) Choline Metabolism Provides Novel Insights into Non-alcoholic Fatty Liver Disease and its Progression. Curr Opin Gastroenterol. 28:159-165. PMID:22134222
Protein Kinase Cα Phosphorylates a Novel Argininosuccinate Synthase Site at Serine 328 during Calcium-dependent Stimulation of Endothelial Nitric-oxide Synthase in Vascular Endothelial Cells
Haines, RJ, Corbin, KD, Pendleton, LC, Eichler, DE. (2012) PKCα Phosphorylates a Novel Argininosuccinate Synthase Site at S328 During Calcium-Dependent Stimulation of eNOS in Vascular Endothelial Cells. J Biol Chem. 287: 26168–26176. PMID:22696221
Insulin transcriptionally regulates argininosuccinate synthase to maintain vascular endothelial function
Haines, RJ, Corbin, KD, Pendleton, LC, Meininger, CJ Eichler, DE. (2012) Insulin transcriptionally regulates argininosuccinate synthase to maintain vascular endothelial function. Biochem Biophys Res Commun. 421:9-14.
Choline Dehydrogenase Polymorphism RS12676 is a Functional Variation and is Associated with Changes in Human Sperm Cell Function
Johnson, A.R., Lao, S., Wang, T., Galanko, J.A., Zeisel, S.H. (2012) Choline dehydrogenase polymorphism rs12676 is a functional variation and is associated with changes in human sperm cell function. PLoS ONE. 7(4): e36047. PMID: 22558321.
Perinatal Epigenetic Determinants of Cognitive and Metabolic Disorders
Lupu DS and Niculescu MD (2012) Perinatal Epigenetic Determinants of Cognitive and Metabolic Disorders. Aging and Disease 3
Maternal-linolenicacid availability during gestation and lactation alters the postnatal hippocampal Development in the Mouse Offspring
Niculescu MD, Lupu, DS and Craciunescu CN (2012) Perinatal manipulation of α-linolenic acid intake induces epigenetic changes in maternal and offspring livers. The FASEB Journal 27