News
Our research not only influences the scientific community, but the general public as well. We strive to share our discoveries with everyone. Read some of our latest articles on what is happening at the Nutrition Research Institute.
Clinical Studies at the NRI
The Nutrition Research Institute is committed to conducting innovative, basic and translational science to support the understanding of individualized nutrition. These advances in science promote the prevention and reduction of chronic disease and obesity. To move...
NRI Faculty Elected as AHA Fellow
The NRI is proud to announce that Saroja Voruganti, Ph.D., assistant professor in the Department of Nutrition at UNC Chapel Hill, has been elected a Fellow with the American Heart Association. Dr. Voruganti is one of 17 American Heart Association Fellows from several...
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Tsybovsky Y, Malakhau Y, Strickland KC, Krupenko SA.
Chem Biol Interact. 2013 Feb 25;202(1-3):62-9. doi: 10.1016/j.cbi.2012.12.015. Epub 2013 Jan 5.
PMID: 23295222
JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1
JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1.
Prakasam A, Ghose S, Oleinik NV, Bethard JR, Peterson YK, Krupenko NI, Krupenko SA.
Cell Death Dis. 2014 Jul 31;5:e1358. doi: 10.1038/cddis.2014.316.
PMID: 25077544
A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization
A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization.
DebRoy S, Kramarenko II, Ghose S, Oleinik NV, Krupenko SA, Krupenko NI.
PLoS One. 2013 Jul 30;8(7):e70062. doi: 10.1371/journal.pone.0070062. Print 2013.
PMID: 23936142
Activation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress
Activation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress.
Hoeferlin LA, Oleinik NV, Krupenko NI, Krupenko SA.
Genes Cancer. 2011 Sep;2(9):889-99. doi: 10.1177/1947601911432495.
PMID: 22593801
Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation
Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation.
Oleinik NV, Helke KL, Kistner-Griffin E, Krupenko NI, Krupenko SA.
J Biol Chem. 2014 Sep 19;289(38):26383-94. doi: 10.1074/jbc.M114.569657. Epub 2014 Aug 1.
PMID: 25086046
Molecular mechanisms underlying the potentially adverse effects of folate
Molecular mechanisms underlying the potentially adverse effects of folate.
Strickland KC, Krupenko NI, Krupenko SA.
Clin Chem Lab Med. 2013 Mar 1;51(3):607-16. doi: 10.1515/cclm-2012-0561. Review.
PMID: 23241610
ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A
ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A.
Oleinik NV, Krupenko NI, Krupenko SA.
Oncogene. 2010 Nov 25;29(47):6233-44. doi: 10.1038/onc.2010.356. Epub 2010 Aug 23.
PMID: 20729910