February 18, 2016 • Scientists at the UNC Chapel Hill Nutrition Research Institute are developing a “whole health” message for pregnant mothers emphasizing evidence-based, nutritional research that empowers them to make their own decisions on everything from drinking to dietary choices.
February 1, 2016 • The Zeisel laboratory at the UNC Nutrition Research Institute (NRI) is well known for defining the importance of the nutrient choline in infant brain development. They discovered that choline in mother’s diet during pregnancy is extremely important for optimal brain development in her baby. But, is this the only time in life that choline can improve brain function? Could teenagers eat extra choline to help their school performance?
January 28, 2016 • Cereal, pasta, bread, cookies – what do they have in common? The answer is “folic acid,” a synthesized form of a naturally occurring B vitamin called folate. Folate occurs naturally in some foods such as green leafy vegetables, avocados, red meat and lentils. Almost any processed food made with flour has folic acid.
January 2, 2016 • Children of mothers whose diet during pregnancy was deficient in the essential nutrient choline have lower performance on cognitive tests. Cognition is rooted in the brain’s cortex, but a direct link between maternal dietary choline levels and cortical development in offspring had not been demonstrated. Experimental evidence of this link, and identification of a physiological mechanism, would greatly enhance our understanding of the importance of proper nutrition during pregnancy.
November 24, 2015 • From the desk of: David Horita, Ph.D.
THE STUDY
In a recently published paper1, NRI investigator Phil May and colleagues showed that the prevalence of fetal alcohol syndrome (FAS) and partial fetal alcohol syndrome (PFAS) is two to three times higher than previously estimated.
Dr. May’s study differs from most FAS prevalence studies in its use of active case ascertainment testing methods to estimate prevalence. This technique includes developmental testing of the child and detailed one-on-one interviews of the mother. The interview questions covered alcohol use during pregnancy, but also asked questions related to secondary factors, such as overall drinking history, marital status; socioeconomic status, and diet/nutrition. This approach is much more labor-intensive than the more common survey approach that relies on self-reported alcohol use information. However, it is also more accurate: self-reported alcohol usage surveys often underestimate FAS because of the stigma of drinking during pregnancy.
November 24, 2015 • The research in Dr. Carol L. Cheatham’s Nutrition and Cognition lab focuses on effects of nutrition on brain development and function throughout the lifespan. In her work, she is exploring the importance of certain nutrients and foods to the development, maintenance, and lifelong integrity of the hippocampus and frontal brain areas. Nutrition is integral to fetal and infant brain development, which sets the stage for lifelong learning. At the other end of the spectrum, it is beginning to be evident that nutrition is also important in senescence in that certain nutrients coupled with other healthy lifestyle choices can slow the progression of age-related cognitive decline. Dr. Cheatham has active studies in four age groups; some of that work is summarized here.