Environment and Nutrition
Beginning at conception, environmental factors in health can accumulate over a lifetime and be from sources as broad as geographic location and economic status to specific external sources including physical activity, occupation, risky behaviors and diet. But some of these factors, especially in terms of diet are highly modifiable.
Important research is now being conducted on this concept of the “exposome,” as an environmental complement to the human genome. NRI researchers are learning how diet and other environmental exposures interact with disease and affect responses to treatment.
Publications
Environment and Nutrition Publications
2020
Precision (Personalized) Nutrition: Understanding Metabolic Heterogeneity. Zeisel S
Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches. Zeisel S
2019
Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors. Hursting S
When less may be more: calorie restriction and response to cancer therapy. Hursting S
Energy balance and obesity: what are the main drivers? Hursting S
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Early-Life Predictors of Fetal Alcohol Spectrum Disorders. May P
Alcohol’s Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status. Smith S
2018
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms. Hursting S
Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention. Hursting S
2017
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype. Krupenko S
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Zeisel S
2016
CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. Krupenko N
Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. Smith S
Impact of a western diet on the ovarian and serum metabolome. Sumner S
Metabolomics enables precision medicine: “A White Paper, Community Perspective”. Sumner S
Related News
The Ironies of Iron During Pregnancy
August 28, 2017 – Iron is listed by the American Pregnancy Association as one of the nutrients essential for healthy fetal development. Why? Because a lack of iron, a mineral naturally found in foods like meat, seafood and vegetables, directly impacts the development of the fetal brain. Iron also prevents anemia, low birth weight and premature delivery. Unfortunately, 22 percent of US women in their childbearing years are iron deficient, says Susan Smith, PhD, deputy director of science at the UNC Nutrition Research Institute on the NC Research Campus.
UNC-CH Nutrition Research Institute Graduate Student Housing Opens Steps Away from NCRC Main Campus
June 27, 2017 • The Nutrition Research Institute (NRI) offers unique learning and work experiences for graduate students in the fields of nutrigenomics and metabolomics. Our research relies, in fact, on the work these students do. But until recently the institute has been short on student housing, creating hardship for those who wished to study and work here. That has changed with the opening of five newly refurbished houses a short walk from the institute and the rest of the North Carolina Research Campus, offering both short- and long-term student housing options.
August 2017
Precision Nutrition Needed For Healthy Military Muscles By Allan Maurer, NCBiotech Writer Eat colorful meals and make sure you get enough choline. That’s the key advice two nutrition experts offered during lunch at the Medical, BioMedical & BioDefense: Support the...
Maternal Vitamin D For Preventing Autism
July 27, 2017 – Vitamin D deficiency in pregnant moms is shown to negatively affect fetal growth and children’s health in the long run. Deficient gestational vitamin D status is surprisingly high both globally and in the US. One of the findings that draws attention is the role of vitamin D during pregnancy in children’s chances of developing Autism Spectrum Disorders (ASD). Vitamin D is acquired through sun exposure or food intake. The circulating form of vitamin D can travel through the fetal-placental barrier, thus, developing babies depend solely on their mothers for getting this beneficial nutrient.
Precision Nutrition Needed for Healthy Military Muscles
July 27, 2017 • “Eat colorful meals and make sure you get enough choline.” That’s the key advice offered by David Nieman, Dr.PH, FACSM, Director of the Appalachian State University Human Performance Laboratory; and Steven Zeisel, M.D., Ph.D., Director of the University of North Carolina at Chapel Hill’s Nutrition Research Institute. during lunch at the Medical, BioMedical & BioDefense: Support the Warfighter symposium in Chapel Hill in June. These were among several surprising findings […]
Cheatham Named to Education Board
July 27, 2017 – Carol L. Cheatham, PhD, has been selected to join the Education Board at the American Health Council. The council, comprising leaders and contributors from all areas of healthcare, is America’s leading organization in health awareness and advancement. Dr. Cheatham will share her knowledge and expertise on the effects of nutrition on brain development and function. […]