Sandra M. Mooney, PhD
Associate Professor of Nutrition
Sandra Mooney, PhD joined the UNC Chapel Hill Nutrition Research Institute in August 2018 as an Associate Professor of Nutrition. Her research program investigates the effect(s) of environment and genes on brain development, with a focus on prenatal alcohol exposure. Current studies use animal models to understand how nutritional needs change after alcohol exposure, thereby increasing the chances that modifying (or personalizing) nutrition will optimize growth and development. This work is supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Dr. Mooney received her Ph.D. from the University of Otago in New Zealand.
The overall theme of Dr. Mooney’s research is to understand normal brain development, how exposure to alcohol (and other drugs or experiences) disrupts this, what the behavioral outcomes are, and whether simple nutrition-based interventions can improve outcomes. Developmental exposure to ethanol profoundly affects development of the nervous system. Indeed, fetal alcohol exposure is described as the primary known cause of mental retardation, and recent estimates suggest that 2-5% of US children can be diagnosed with a Fetal Alcohol Spectrum Disorder.
Functional Connectivity and Metabolic Alterations in Medial Prefrontal Cortex in a Rat Model of Fetal Alcohol Spectrum Disorder: A Resting-State Functional Magnetic Resonance Imaging and in vivo Proton Magnetic Resonance Spectroscopy Study.