Sergey A. Krupenko, PhD
Professor of Nutrition
sergey_krupenko@unc.edu
704-250-5053
Amira Abdellatef, PhD
Postdoctoral Research Associate, S. Krupenko Lab
Amira A. Abdellatef is currently working as a Post-Doctoral Research Associate at Sergey A. Krupenko Lab, Nutrition Research Institute (NRI), the University of North Carolina at Chapel Hill. Dr. Amira completed her Ph.D. in cancer biology and immunology from the Graduate School of Medicine and Pharmaceutical Sciences, the University of Toyama, Japan in 2021, under the supervision of Prof. Yoshihiro Hayakawa. Before joining NRI, she completed her Research Scholar training at the University of Toyama, Japan, and a postdoctoral appointment at Julius L. Chambers Biomedical/Biotechnology Research Institute (BBRI), North Carolina Central University (NCCU), under the mentorship of Prof. Xiaohe Yang. She is a recent recipient of the Award of Female Researchers of the University of Toyama, Japan. Her research project focuses on the function of folate enzymes ALDH1L1 and ALDH1L2 in cellular metabolism and their association with human diseases. Her project utilizes cell culture and mouse models to answer questions about the role of folate metabolizing enzymes and dietary folate in liver and brain functions, tumorigenesis, cancer progression, and metastasis. She has co-authored many peer-reviewed articles and had several poster/oral presentations at international and local conferences. Outside of the academia, she enjoys listening to music, watching movies, walking, swimming, and cooking.
Rhyston Broadhurst
Research Technician, S. Krupenko Lab
Rhyston earned a Bachelor’s of Science in Biochemistry from Texas A&M University in December of 2022. Rhyston joined the NRI in July of 2023 working in Dr. Krupenko’s Lab. In his free time, Rhyston enjoys reading, working out, and playing Ultimate Frisbee.
Halle Fogle
Graduate Student, S. Krupenko Lab
Halle earned a Bachelor’s of Science in Biology and Minor in Anthropology at St. Mary’s College of Maryland in May 2020. After moving to Charlotte, Halle joined the NRI in August 2020 as a Research Technician in Dr. Sergey Krupenko’s Lab, where she studies the role of folate in liver function and cancer disease. Halle plans to further her education in the research field within the next couple of years.
Bryan Munoz, PhD
Postdoctoral Research Associate, S. Krupenko Lab
Bryan Munoz joined the S. Krupenko lab in February 2022 as a postdoctoral research associate. Dr. Munoz attended EARTH University in Costa Rica majoring in Agricultural Sciences, then continued his graduate career at the University of Nebraska - Lincoln and North Carolina State University, where he earned his doctoral degree in Nutrition and Horticultural Sciences. Dr. Munoz has worked with plants his entire life, and is interested in learning new techniques in molecular biology and animal models in his appointment in the S. Krupenko lab.
David Raines
Research Technician, S. Krupenko Lab
David Raines graduated from The College of Wooster in May 2014 with a bachelor’s in biology. He’s very excited to be working as a laboratory technician in Sergery Krupenko’s lab. David enjoys spending his free time outdoors herping for reptiles and amphibians; hiking, and backpacking.
Hansuk Ryu, MD, PhD
Visiting Scholar, S. Krupenko Lab
Hansuk Ryu joined the S. Krupenko lab in September 2023 as a visiting scholar. Dr Hansuk earned a Bachelor of Medicine at Hanyang University in South Korea. He received his doctoral degree from Seoul National University College of Medicine in South Korea. He is a pathologist and plans to work with cancer and metabolism in Dr. Sergey Krupenko’s Lab
Folate is Essential, But Don’t Overdo It
Folate is a water-soluble vitamin, naturally found in many foods. Folate helps to make DNA and RNA and is involved in metabolism of amino acids. It is needed to produce healthy red blood cells and plays a key role in removing homocysteine, a molecule that can exert...
UNC nutrition experts uncover structure of enzyme that could aid in disease treatment, prevention
This article was published originally by the Gillings School of Global Public Health on January 25, 2022. New findings from researchers at the UNC Nutrition Research Institute (NRI) have revealed the structure of an enzyme that plays a key role in predicting whether a...
Keep the Fireworks Going: NRI Student Success is Explosive!
This summer, NRI students continue to shine bright and have been recognized for their endeavors both on the University level and nationally! Congratulations to Halle Fogle, an incoming graduate student in the Sergey Krupenko Lab. Halle recently received a UNC Gillings...
NIH Grant To Study Gene Mutation Associated with Rare Disease
March 22, 2019 – Sergey A. Krupenko, PhD, professor of nutrition at the UNC Nutrition Research Institute (NRI), has been awarded a $2.4 million grant from the National Institutes of Health for his research project, “Regulation of Mitochondrial Function by Folate...
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The Role of Single-Nucleotide Polymorphisms in the Function of Candidate Tumor Suppressor ALDH1L1.
Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver.
Deleterious mutations in ALDH1L2 suggest a novel cause for neuro-ichthyotic syndrome.
Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression.