Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
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The UNC Nutrition Research Institute is proud to celebrate Natalia Krupenko, PhD, and Stephen Hursting, PhD, MPH, who have been named 2026 Excellence in Nutrition Fellows of the American Society for Nutrition.
The FASN designation recognizes distinguished members of ASN for their ongoing contributions to the field of nutrition and sustained engagement in the nutrition community. For Krupenko and Hursting, the honor reflects not only individual achievement, but also the long-term impact of research that is helping shape how scientists understand the relationship between nutrition, metabolism, chronic disease, and lifelong health.
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Halle Meyer’s journey at the UNC Nutrition Research Institute began in 2020, when she joined the institute as a 21-year-old research technician in the lab of Sergey Krupenko, MD, PhD. Nearly six years later, she successfully defended her dissertation, earned her PhD in Nutrition from UNC-Chapel Hill, and leaves the NRI with not only scientific expertise, but a deep appreciation for the community and mentorship that shaped her along the way.
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