Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
NRI Faculty Member Receives Prestigious Award
Philip A. May, Ph.D., is this year’s recipient of the Henry Rosett Award, in recognition of his substantial contribution researching the field of Fetal Alcohol Spectrum Disorders (FASD). Dr. May received the award at the annual meeting of the FASD Study Group of the Research Society on Alcoholism in June.
Firsts for an NRI Young Scientist
Tracey He has the distinction of being the first NRI researcher to have earned a master’s degree while working in an NRI lab. Her story is one of passion and dedication.
Study Shows Mother’s Diet Affects Child’s Genes
NRI director Dr. Steven Zeisel is co-author of a study showing that a mother’s diet before conception can permanently affect how her child’s genes function. The study has been published in Nature Communications.
Berries and Brain: Partners in Life and Longevity
Carol Cheatham, Ph.D. and Kelly Sheppard, Ph.D.
Uric Acid: A New Look at an Old Risk Factor for Gout and Cardio-renal Disease
Saroja Voruganti, Ph.D.
Appetite for Life SoundBites Spring 2014
In this Issue:
– Top Ten Reasons to Give
– Dr. Martin Kohlmeier – Teaching Nutrition and Physical Activity in Medical School
– Appetite for Life
– NRI Celebrates 5 Years
– North Carolina Science Festival
and more!
