Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Status of nutrition education in medical schools
Status of nutrition education in medical schools.
Adams KM, Lindell KC, Kohlmeier M, Zeisel SH.
Am J Clin Nutr. 2006 Apr;83(4):941S-944S.
PMID: 16600952
The evolution of Nutrition in Medicine, a computer-assisted nutrition curriculum
The evolution of Nutrition in Medicine, a computer-assisted nutrition curriculum.
Lindell KC, Adams KM, Kohlmeier M, Zeisel SH.
Am J Clin Nutr. 2006 Apr;83(4):956S-962S.
PMID: 16600955
Nutrition education in U.S. medical schools: latest update of a national survey
Nutrition education in U.S. medical schools: latest update of a national survey.
Adams KM, Kohlmeier M, Zeisel SH.
Acad Med. 2010 Sep;85(9):1537-42. doi: 10.1097/ACM.0b013e3181eab71b.
PMID: 20736683
Association between MTHFR C677T, MTHFR A1298C and MS A2756G polymorphisms and risk of cervical intraepithelial neoplasia II/III and cervical cancer: a meta-analysis
Association between MTHFR C677T, MTHFR A1298C and MS A2756G polymorphisms and risk of cervical intraepithelial neoplasia II/III and cervical cancer: a meta-analysis.
Zhu J, Wu L, Kohlmeier M, Ye F, Cai W.
Mol Med Rep. 2013 Sep;8(3):919-27. doi: 10.3892/mmr.2013.1589. Epub 2013 Jul 16.
PMID: 23864153
Capacity building in nutrition science: revisiting the curricula for medical professionals
Capacity building in nutrition science: revisiting the curricula for medical professionals.
Dimaria-Ghalili RA, Edwards M, Friedman G, Jaferi A, Kohlmeier M, Kris-Etherton P, Lenders C, Palmer C, Wylie-Rosett J.
Ann N Y Acad Sci. 2013 Dec;1306:21-40. doi: 10.1111/nyas.12334. Review.
PMID: 24329516
Translational research in complementary and alternative medicine
Translational research in complementary and alternative medicine. Jia W, Kohlmeier M, Lu A, Zeng R. Evid Based Complement Alternat Med. 2013;2013:296817. doi: 10.1155/2013/296817. Epub 2013 Oct 9. No abstract available. PMID: 24223614