Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
Innovation. Discovery. Impact.
Fiscal Year 2021 was a landmark year in the history of the UNC Nutrition Research Institute: We transitioned directorship while continually adapting to safety requirements to operate our world-class center during a worldwide pandemic. We are delighted to share with...
Student Success at the NRI: Alleigh Wiggs, Breast Cancer Researcher and Advocate
Congratulations to Alleigh Wiggs, a student researcher with the Sumner Lab, whose research on the effects of diet and exercise on endogenous estrogens and subsequent breast cancer risk in postmenopausal women was recently published in Frontiers in Endocrinology....
Dr. Susan M. Smith Named Inaugural Dickson Foundation – Harris Teeter Distinguished Professor in Nutrition
Susan M. Smith, PhD, has been named the inaugural holder of The Dickson Foundation – Harris Teeter Distinguished Professorship in Nutrition. Smith, who joined the UNC-Chapel Hill faculty in 2016, is a professor of Nutrition at the Gillings School of Global Public...
Metabolic clues could serve as early predictors of pregnancy complications, inform nutritional intervention
Published on the Gillings School of Global Public Health website June 18, 2021. Some of the most common complications that moms and babies face during pregnancy include high blood pressure, preeclampsia and preterm birth, but predicting who might be at risk is still...
Could nutrient cocktails play a role in diminishing addiction, reducing adverse effects of substance abuse?
Published on The Gillings School of Global Public Health website May 19, 2021. Research has shown that using illicit drugs, including opiates and opioids, can disrupt a person’s metabolism and impact neurological and behavioral function. Experts at the UNC Gillings...
Keep the Fireworks Going: NRI Student Success is Explosive!
This summer, NRI students continue to shine bright and have been recognized for their endeavors both on the University level and nationally! Congratulations to Halle Fogle, an incoming graduate student in the Sergey Krupenko Lab. Halle recently received a UNC Gillings...