Microbiome and Nutrition
The complex community of bacteria, yeasts and viruses living in our intestines, collectively known as the gut microbiome, is shaped, in part, by what we eat. Genetics, environment, and other factors also influence an individual’s microbial community. Research at the NRI investigates these complex relationships and their impact on disease risk. We use animal models and bioinformatics to study the associations between nutritional metabolites, gut microbiome, and health. What happens in the gut doesn’t stay in the gut. Your microbiome can play a role in cardiovascular disease, obesity and diabetes, and even cancer. Our team envisions a future where analysis of your microbiome can determine disease risk, and medical foods can be prescribed to treat and prevent disease by regulating the microbiome.
Publications
Microbiome and Nutrition Publications
2020
Population studies of TMAO and its precursors may help elucidate mechanisms. Meyer K
2019
Association of dietary patterns with the gut microbiota in older, community-dwelling men. Meyer K
2018
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Meyer K
Human microbiota, blood group antigens, and disease. Sumner S
2017
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease. Zeisel S
2016
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk. Meyer K
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice. Sumner S
Related News
What We're Learning about Mom's Nutrition and Alcohol
January 1, 2017 • Dr. Phil May’s research group at the NRI studies the prevalence of Fetal Alcohol Spectrum Disorders (FASD) in humans. The recent addition to the NRI faculty of Dr. Susan Smith now provides an avenue toward understanding how maternal nutrition might affect the relationship between alcohol and FASD through the use of animal models. Two recent papers from these research groups illustrates this synergy […]
The Latino Eyelid: Anthropometric Analysis of a Spectrum of Findings.
Comparison of 2 models for gene– environment interactions: an example of simulated gene–medication interactions on systolic blood pressure in family-based data
Genome-wide association of trajectories of systolic blood pressure change
Renowned Scientist Joins Nutrition Research Institute
November 30, 2016 • Susan Sumner, PhD joins the UNC Nutrition Research Institute (NRI) on December 1, 2016, as a Professor of metabolomicsNutrition. Dr. Sumner is working to make personalized medicine a reality through metabolomics. Metabolomics involves measuring thousands of metabolites in cells, tissues, and biological fluids.
December 2015
It’s #GivingTuesday, a global day dedicated to celebrating generosity and to giving to a cause you care about. Please consider a gift to the Nutrition Research Institute. Healthy Brain Function Tied to Nutrition A variety of research on babies and their...