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University of North Carolina at Chapel Hill
NC Research Campus
Several recent studies linked increased levels of a metabolic product of dietary choline with higher risk of cardiovascular disease (CVD) through a mechanism that involved gut microbiota-produced trimethylamine oxide (TMAO).
According to the CDC, sugar-sweetened beverages are the largest source of added sugar in the average American’s diet, and the Dietary Guidelines for Americans recommend individuals consume no more than ten percent of calories per day from processed or added sugar.
Recruiting: African American, Hispanic and Caucasian, 30 to 50 year olds.
Study Purpose: High uric acid in the blood increases the risk of gout, kidney and heart disease. This study investigates whether each individual responds to sugar-sweetened beverages differently, due to their differing ethnicities and genetic backgrounds.